Degree of handedness and cerebral dominance
Degree of handedness and cerebral dominance
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DOI：
10.1212/01.wnl.0000219623.28769.74
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发表时间：
2006-06-27
期刊：
影响因子：
9.9
通讯作者：
Devinsky, Orrin
中科院分区：
文献类型：
--
作者：
Isaacs, Keren L.;Barr, William B.;Devinsky, Orrin
目的：探讨癫痫患者利手程度与大脑半球语言优势的关系。方法：采用改良的爱丁堡利手问卷，采用颈内动脉异巴比妥术，对174例癫痫手术患者的利手程度与大脑半球语言优势之间的关系进行了研究。结果：非典型语言优势的发生率与左撇子的程度呈线性关系，从强右利手(侧向商[LQ]=+100)的9%上升到双灵巧者的46%和强左利手(LQ=-100)的69%。结论：非典型语言优势的发生率不仅与利手的使用方向有关，还与利手的程度有关。此外，语言优势的方向因癫痫发作的大脑半球和利手程度而不同。左旋家族史可能对非典型显性遗传的可能性有额外的影响。
Objective: To examine the relationship between the degree of handedness and hemispheric language dominance in patients with epilepsy. Methods: The authors examined the relationship between degree of handedness and hemispheric language dominance in 174 epilepsy surgery candidates using the intracarotid amobarbital procedure and results from a modified version of the Edinburgh Handedness Inventory. Results: The incidence of atypical language dominance increased linearly with the degree of left-handedness, from 9% in strong right-handers (laterality quotient [LQ] = +100) to 46% in ambidextrous individuals and 69% in strong left-handers (LQ = -100). Conclusions: The incidence of atypical language dominance depends not only on the direction but also on the degree of handedness. In addition, direction of language dominance varies with hemisphere of seizure focus and degree of handedness. A familial history of sinistrality may have an additional effect on the likelihood of atypical dominance.