Mitomycin as adjunct chemotherapy with trabeculectomy.

Mitomycin as adjunct chemotherapy with trabeculectomy.
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丝裂霉素作为小梁切除术的辅助化疗。

DOI:
10.1016/s0161-6420(91)32293-0
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发表时间:
1991
期刊:
影响因子:
13.7
通讯作者:
Steven S. Palmer
Steven S. Palmer
中科院分区:
医学1区
文献类型:
--
作者:
Steven S. Palmer

文献摘要

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初步经验报告使用丝裂霉素,以改善预后小梁切除术,否则被认为是不可能成功的。该药物在标准小梁切除术过程中术中应用。如果压力降低到预定的目标水平,则认为手术是成功的,唯一的视力下降被认为是基于白内障的发展,并且没有杯状或视野丧失的进展。随访6 ~ 42个月,总成功率为84%。
Preliminary experience is reported in using mitomycin to improve the prognosis in trabeculectomy operations considered otherwise likely not to succeed. The medication is applied intraoperatively during an otherwise standard trabeculectomy procedure. Surgery was considered successful if the pressure was lowered to a predetermined target level, the only vision reduction was believed to be on the basis of cataract development, and there was no progression of cupping or visual field loss. With a follow-up of 6 to 42 months, the overall success rate is 84%.