Computational virtual evaluation of the effect of annuloplasty ring shape.
Computational virtual evaluation of the effect of annuloplasty ring shape.
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DOI：
10.1002/cnm.2831
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发表时间：
2017-06
影响因子：
2.1
通讯作者：
Kim H
中科院分区：
文献类型：
--
作者：
Choi A;McPherson DD;Kim H
Mitral regurgitation (MR) is a result of mitral valve (MV) pathology. Its etiology can be categorized as degenerative or functional MR. Ring annuloplasty aims to reconfigure a dilated mitral annulus to its normal size and shape. We investigated the effect of annuloplasty ring shape on MR outcome using our established 3D echocardiography-based computational MV evaluation protocols. Virtual patient MV models were created from 3D transesophageal echocardiographic data in patients with MR due to mitral annular dilation. Two distinct annuloplasty rings (Physio II and GeoForm) were designed and virtually implanted to the patient MVs. Dynamic FE simulations of MV function were performed for each MV following virtual ring annuloplasty of either ring, and physiologic and biomechanical characteristics of MV function were compared. Excessive stress values appeared primarily in the mid-anterior and mid-posterior regions, and lack of leaflet coaptation was found in pre-annuloplasty patient MVs. Both rings demonstrated marked reduction of stresses and efficient leaflet coaptation. The Physio II ring demonstrated more evenly distributed stress reduction across the leaflets and annulus compared to the GeoForm ring. Conversely, the highly non-planar curvature of the GeoForm ring more effectively increased leaflet coaptation compared to the Physio II ring. This indicates that the shape of annuloplasty ring affects post-annuloplasty physiologic and biomechanical conditions, which can lead to tissue alteration over a longer period of time following ring annuloplasty. This virtual ring annuloplasty simulation strategy provides detailed physiologic and biomechanical information and may help better plan the optimal ring selection and improved patient-specific MV repairs.
