Iridium-catalyzed C-H amidation of s-tetrazines
Iridium-catalyzed C-H amidation of s-tetrazines
复制标题
铱催化s-四嗪的C-H酰胺化反应
DOI：
10.1039/d0cc01647k
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发表时间：
2020
影响因子：
4.9
通讯作者：
Xu Hongtao
中科院分区：
文献类型：
--
作者：
Xiong Huan;Gu Yuang;Zhang Shuning;Lu Fengping;Ji Qun;Liu Lili;Ma Peixiang;Yang Guang;Hou Wei;Xu Hongtao
An efficient, selective and scalable C–H amidation of s-tetrazines under iridium(III) catalysis is reported. This reaction features a broad substrate scope, high functional group tolerance, and air and water tolerance. This reaction also shows great potential for the rapid preparation of tri- and tetra-functional building blocks, which can be applied either in bioconjugation or synthesis of DNA-encoded library.
