Phase locking in the mammalian circadian clock

Phase locking in the mammalian circadian clock
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哺乳动物生物钟的锁相

DOI:
10.1109/cdc.2000.912097
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发表时间:
2000
期刊:
Proceedings of the 39th IEEE Conference on Decision and Control (Cat. No.00CH37187)
影响因子:
--
通讯作者:
C. Martin
C. Martin
中科院分区:
--
文献类型:
--
作者:
J. Miller;W. Dayawansa;P. Hallgren;C. Martin

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哺乳动物体内存在一种内在的定时机制,众所周知,昼夜节律是在下丘脑的一个双侧结构中产生的,这个结构被称为视交叉上核(Suprachaismatic Nucleus, SCN),由16000个神经元组成。单独地,每个SCN神经元的行为就像一个时钟,神经元的集合能够产生具有精确定时模式的良好同步和锁相时钟信号。本文利用对称条件下的Hopf分岔理论,从系统论的角度解释了SCN的功能性和锁相性。
Existence of an internal timing mechanism in mammals has been well established and it is known that the circadian rhythm is generated in a bilateral structure contained in the hypothalamus called the Suprachaismatic Nucleus (SCN) consisting of 16000 neurons. Individually, each SCN neuron behaves like a clock, and the ensemble of neurons are capable of producing well synchronized and phase locked clock signals with precise timing patterns. In the article, the theory of Hopf bifurcations in the presence of symmetries, is used to explain the functionality and phase locking of the SCN from a systems theory viewpoint.
DOI: 10.1006/jtbi.1998.0667
发表时间: 1998-06-21
影响因子: 2
作者:
Jewett, ME;Kronauer, RE
通讯作者: Kronauer, RE