EEG differences in children as a function of resting-state arousal level
EEG differences in children as a function of resting-state arousal level
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DOI：
10.1016/s1388-2457(03)00343-2
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发表时间：
2004-02-01
影响因子：
4.7
通讯作者：
Ploskova, E
中科院分区：
文献类型：
--
作者：
Barry, RJ;Clarke, AR;Ploskova, E
目的：本研究旨在探讨对当前有关注意力缺陷/多动障碍 (AD/HD) 的文献具有重大影响的理论立场的基础，即脑电图中 θ 与 β 功率的比值（θ/β 比值）代表中枢神经系统 (CNS) 的唤醒。方法：研究了正常右手男孩的静息态地形脑电图活动作为 CNS 唤醒的函数。唤醒是根据皮肤电活动来定义的，在心理学中作为中枢神经系统唤醒的衡量标准有着悠久的历史。结果：相对 delta、theta 和 beta 功率以及 theta/beta 比率在年龄匹配的组之间没有显着差异，这些组在皮肤电导水平和非特异性皮电波动方面存在显着差异。高唤醒组的相对 α 功率水平明显较低，特别是在后部和半球区域，这些区域的 α 频率较高。结论：这些数据未能支持 θ/β 比值与中枢神经系统唤醒之间的理论联系。需要进一步的工作来理清唤醒和任务相关激活的不同相关性，特别是在认知和注意力处理方面。意义：这项研究的结果除了阐明中枢神经系统唤醒的脑电图标记的性质外，对我们对 AD/HD 的理解也具有重要意义，因为它们需要重新评估当前的疾病模型。 (C) 2003 年国际临床神经生理学联合会。由爱思唯尔爱尔兰有限公司出版。保留所有权利。
yObjective: This study aimed to explore the basis of a theoretical position which has major impact in the current literature on attention-deficit/hyperactivity disorder (AD/HD)-that the ratio of theta to beta power in the EEG (the theta/beta ratio) represents central nervous system (CNS) arousal.Methods: Resting state topographic EEG activity was investigated as a function of CNS arousal in normal right-handed boys. Arousal was defined in terms of electrodermal activity, which has a long history in Psychology as a measure of CNS arousal.Results: Relative delta, theta, and beta power, and the theta/beta ratio, failed to differ significantly between age-matched groups which differed markedly in skin conductance level and non-specific electrodermal fluctuations. The high-arousal group showed significantly lower levels of relative alpha power, particularly in posterior and hemispheric regions, with higher alpha frequencies in these areas.Conclusions: These data fail to support the theoretical linkage between the theta/beta ratio and CNS arousal. Further work is needed to disentangle the different correlates of arousal and task-related activation, particularly in cognitive and attentional-processing terms.Significance: The outcomes of this study, in addition to clarifying the nature of EEG markers of CNS arousal, have important implications for our understanding of AD/HD), as they require re-evaluation of current models of the disorder. (C) 2003 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.