Adverse impact of sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome
Adverse impact of sexual dysfunction in chronic prostatitis/chronic pelvic pain syndrome
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DOI：
10.1016/j.urology.2007.08.043
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发表时间：
2008-01-01
期刊：
影响因子：
2.1
通讯作者：
Krieger, John N.
中科院分区：
文献类型：
--
作者：
Lee, Shaun Wen Huey;Liong, Men Long;Krieger, John N.
目的 研究初级保健转诊人群中性功能障碍的患病率、特征和影响。方法 从普通泌尿外科诊所招募寻求慢性前列腺炎/慢性盆腔疼痛综合征 (CP/CPPS) 治疗的参与者。受试者完成了美国国立卫生研究院慢性前列腺炎症状指数、国际勃起功能指数 5 以及华盛顿大学症状评分中的选定问题。还获得了有关人口统计以及医疗和治疗史的更多信息。性功能障碍被定义为自我报告的勃起功能障碍 (ED) 或射精困难，或两者兼而有之。 结果 在 296 名 CP/CPPS 参与者中，214 名 (72.3%) 报告有性功能障碍。美国国立卫生研究院慢性前列腺炎症状指数总分，有性功能障碍的参与者平均为 22.5 +/- 6.9，而没有报告性功能障碍的参与者为 20.4 +/- 7.8 (P = 0.03)。在 214 名患有性功能障碍的参与者中，54 名（25.0%）仅抱怨 ED，71 名（33.4%）仅抱怨射精困难，89 名（41.6%）同时抱怨 ED 和射精困难。与没有性功能障碍的男性相比，同时报告 ED 和射精困难的男性报告有更严重的 CP/CPPS 症状（方差分析，P = 0.042）和更差的生活质量（方差分析，P = 0.006）。结论 近四分之三的 CP/CPPS 患者报告有性功能障碍。与其他 CP/CPPS 患者相比，患有 CP/CPPS 和性功能障碍的患者的症状明显更差，尤其是生活质量更差。性功能障碍值得考虑作为 CP/CPPS 的一个重要方面和一个潜在的结果衡量标准。
OBJECTIVES To examine the prevalence, characteristics, and impact of sexual dysfunction in our primary care referral population.METHODS Participants seeking treatment for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) were recruited from general urology clinics. The subjects completed the National Institutes of Health-Chronic Prostatitis Symptom Index, International Index of Erectile Function-5, and selected questions from the University of Washington Symptom Score. Additional information on demographics and medical and treatment history were also obtained. Sexual dysfunction was defined as self-reported erectile dysfunction (ED) or ejaculatory difficulty, or both.RESULTS Of 296 participants with CP/CPPS, 214 (72.3%) reported sexual dysfunction. The National Institutes of Health-Chronic Prostatitis Symptom Index total score averaged 22.5 +/- 6.9 for participants with sexual dysfunction compared with 20.4 +/- 7.8 for participants who did not report sexual dysfunction (P = 0.03). Of the 214 participants with sexual dysfunction, 54 (25.0%) complained of ED only, 71 (33.4%) complained of ejaculatory difficulties only, and 89 (41.6%) complained of both ED and ejaculatory difficulties. Men reporting both ED and ejaculatory difficulty reported worse CP/CPPS symptoms (analysis of variance, P = 0.042) and worse quality of life (analysis of variance, P = 0.006) than men without sexual dysfunction.CONCLUSIONS Sexual dysfunction was reported by almost three quarters of patients with CP/CPPS. Patients with CP/CPPS and sexual dysfunction experienced substantially worse symptoms, particularly worse quality of life, than other patients with CP/CPPS. Sexual dysfunction merits consideration as an important aspect of CP/CPPS and a potential outcome measure.