The connective tissue component of the caprine arthritis-encephalitis syndrome.
The connective tissue component of the caprine arthritis-encephalitis syndrome.
复制标题
山羊关节炎脑炎综合征的结缔组织成分。
DOI：
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发表时间：
1980
影响因子：
6
通讯作者：
J. B. Henson
中科院分区：
文献类型：
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作者：
T. Crawford;D. S. Adams;R. Sande;J. Gorham;J. B. Henson
本文描述了12只山羊山羊关节炎-脑炎（CAE）的大体和显微镜下结缔组织病变，包括从其中分离出病毒（CAEV）的山羊。病变最常与包括关节、肌腱鞘和滑囊在内的滑膜内衬结构相关，典型表现为滑膜细胞增生、滑膜下单个核细胞浸润、纤维蛋白、纤维质结块、坏死和矿化。滑膜外病变位于肾脏、血管和大脑。这些器官的炎性浸润主要为单核浸润。肝、脾、肾均可见淀粉样蛋白。微生物学技术未能证明病变中有任何细菌、支原体或衣原体。
The gross and microscopic connective tissue lesions in 12 goats with caprine arthritis-encephalitis (CAE) are described, including those from which a virus (CAEV) was isolated. Lesions were most often associated with synovial-lined structures including joints, tendon sheaths, and bursae, and were typified by synovial cell proliferations, subsynovial mononuclear cell infiltration, the presence of fibrin, fibrinous concretions, necrosis, and mineralization. Extrasynovial lesions were located in kidneys, vessels, and brain. The inflammatory infiltrates in these organs were predominantly mononuclear. Amyloid was also found in liver, spleen, and kidney. Microbiologic techniques failed to demonstrate any bacteria, mycoplasma, or chlamydia in the lesions.