Adjunctive use of an anti-oxidant agent to improve resistance of hybrid layers to degradation
Adjunctive use of an anti-oxidant agent to improve resistance of hybrid layers to degradation
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DOI：
10.1016/j.jdent.2010.10.013
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发表时间：
2011-01-01
影响因子：
4.4
通讯作者：
Toledano, Manuel
中科院分区：
文献类型：
--
作者：
Erhardt, Maria Carolina G.;Osorio, Raquel;Toledano, Manuel
目的：确定抗氧化剂（抗坏血酸-AA）对树脂-牙本质粘合抵抗两种粘合剂降解的作用。方法：按照制造商的说明，使用两步蚀刻和冲洗自底漆粘合剂（Single Bond-SB）和两步自蚀刻粘合剂（Clearfil SE Bond-CSE）粘合 48 颗人类磨牙的平坦牙本质表面。一半的样品使用相同的粘合剂粘合，但在其配方中添加了 10% AA。树脂复合材料逐渐构建并切成树脂-牙本质梁 (1.0 mm(2))，并在四种条件下储存：(1) 水中浸泡 24 小时； (2)水浸泡1年； (3)水浸4年； (4) 化学挑战（浸入 10% NaOCl 中 5 小时）。梁在 0.5 毫米/分钟的张力下被拉至失效。使用方差分析和多重比较测试分析平均微拉伸粘合强度 (MTBS) 数据 (P < 0.05)。通过扫描电子显微镜 (SEM) 对脱粘的牙本质束进行分析。结果：24 小时后，无论 AA 的掺入如何，SB 和 CSE 的表现相同。在 CSE 配方中添加 AA 会降低一年储水后的 MTBS，但即使在储水四年后仍保持 SB 粘合强度值。 NaOCl 挑战降低了两种粘合剂的 MTBS，但当将 AA 添加到 SB 中时，这种降低显着降低。结论：在粘合剂配方中添加 AA，在使用 SB 时对树脂-牙本质粘合的抗降解性发挥保护作用。添加抗坏血酸钠可能会影响 CSE 的粘合耐久性。 (C) 2010 Elsevier Ltd. 保留所有权利。
Objective: To determine the role of an anti-oxidant agent (ascorbic acid-AA) on resin-dentin bonds resistance to degradation of two adhesives.Methods: Flat dentin surfaces from 48 human molars were bonded as per manufacturer's instructions with: a two-step etch-and-rinse self-priming adhesive (Single Bond-SB) and a two-step self-etch adhesive (Clearfil SE Bond-CSE). Half of the specimens were bonded with the same adhesives, but after the addition of 10% AA into their formulation. Resin composite build-ups were constructed incrementally and sectioned into resin-dentin beams (1.0 mm(2)) that were stored under four conditions: (1) water immersion for 24 h; (2) water immersion for 1 year; (3) water immersion for 4 years; and (4) chemical challenging (immersion in 10% NaOCl for 5 h). Beams were pulled to failure in tension at 0.5 mm/min. Mean microtensile bond strength (MTBS) data were analysed with ANOVA and multiple comparisons tests (P < 0.05). Analysis of debonded dentin beams was performed by scanning electron microscopy (SEM).Results: After 24 h, SB and CSE performed equally, regardless of AA incorporation. Inclusion of AA on CSE formulation decreased MTBS following one-year water storage, but maintained SB bond strength values even after four years of water storage. NaOCl challenge diminished MTBS for both adhesives, but when AA was added to SB, this reduction was significantly lower.Conclusions: The inclusion of AA on adhesive's formulation exerts a protective role on resin-dentin bonds resistance to degradation when SB is used. Bonding durability of CSE may be compromised by the addition of sodium ascorbate. (C) 2010 Elsevier Ltd. All rights reserved.