Genetics of src: structure and functional organization of a protein tyrosine kinase.
Genetics of src: structure and functional organization of a protein tyrosine kinase.
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src 的遗传学：蛋白酪氨酸激酶的结构和功能组织。
DOI：
10.1007/978-3-642-74697-0_3
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发表时间：
1989
影响因子：
--
通讯作者：
Weber,MJ
中科院分区：
文献类型：
--
作者：
Parsons,JT;Weber,MJ
鸡的一个肿瘤，组织学上是一个梭形细胞肉瘤，自1909年10月以来一直在这个实验室里繁殖，在过去的几个月里已经发展成极端的恶性肿瘤。从接种到易感家禽的胸肌中的一点开始，迅速发展出一个大而坚固的生长;转移发生在内脏;在四到五周内，宿主通常死亡。新生长的行为贯穿于真正的肿瘤，因此，它通过无细胞滤液传播的事实具有特殊的重要性。
A tumor of the chicken, histologically a spindle-celled sarcoma, has been propagated in this laboratory since October 1909, and in the past few months has developed extreme malignancy. From a bit inoculated into the breast muscle of a susceptible fowl there develops rapidly a large, firm growth; metastasis takes place to the viscera; and within four to five weeks often the host dies. The behavior of the new growth has been throughout that of a true neoplasm, for which reason the fact of its transmission by means of a cell-free fIltrate assumes exceptional importance.