Precipitating antifibrinogen antibody appearing after fibrinogen infusions in a patient with congenital afibrinogenemia.
Precipitating antifibrinogen antibody appearing after fibrinogen infusions in a patient with congenital afibrinogenemia.
复制标题
先天性无纤维蛋白原血症患者输注纤维蛋白原后出现抗纤维蛋白原抗体沉淀。
DOI：
10.1016/0002-9343(61)90057-2
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发表时间：
1961
期刊：
影响因子：
--
通讯作者：
J. Boss
中科院分区：
文献类型：
--
作者：
A. Vries;Tuvia Rosenberg;S. Kochwa;J. Boss
在一个16岁的女孩与先天性无纤维蛋白原血症和风湿性心脏瓣膜病的抗纤维蛋白原抗体开发后，反复输注的人血浆组分I的抗体的外观与严重的输液反应，增加血浆纤维蛋白原消失率和皮肤过敏性纤维蛋白原。尸检发现纤维蛋白样病变的心血管系统。
In a sixteen year old girl with congenital afibrinogenemia and rheumatic valvular heart disease an antifibrinogen antibody developed following repeated infusions of human plasma fraction I.The appearance of the antibody was associated with severe infusion reactions, an increase in plasma fibrinogen disappearance rate and skin hypersensitivity to fibrinogen.Postmortem examination revealed fibrinoid lesions of the cardiovascular system.