Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus
Different macro- and micro-rheological properties of native porcine respiratory and intestinal mucus
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DOI：
10.1016/j.ijpharm.2016.06.035
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发表时间：
2016-08-20
影响因子：
5.8
通讯作者：
Lehr, Claus-Michael
中科院分区：
文献类型：
--
作者：
Bokkasam, Harish;Ernst, Matthias;Lehr, Claus-Michael
Aim of this study was to investigate the similarities and differences at macro- and microscale in the viscoelastic properties of mucus that covers the epithelia of the intestinal and respiratory tract. Natural mucus was collected from pulmonary and intestinal regions of healthy pigs. Macro-rheological investigations were carried out through conventional plate-plate rheometry. Microrheology was investigated using optical tweezers. Our data revealed significant differences both in macro- and micro-rheological properties between respiratory and intestinal mucus. (C) 2016 Elsevier B.V. All rights reserved.
