Comparison of volatile sulfur compound concentrations measured with a sulfide detector vs. gas chromatography
Comparison of volatile sulfur compound concentrations measured with a sulfide detector vs. gas chromatography
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DOI：
10.1177/154405910208100211
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发表时间：
2002-02-01
影响因子：
7.6
通讯作者：
Levitt, MD
中科院分区：
文献类型：
--
作者：
Furne, J;Majerus, G;Levitt, MD
Halimeter（R）是一种廉价、简单的仪器，用于测量总呼吸挥发性硫化合物（VSC），其准确性尚未得到充分测试。我们将Halimeter（R）测量结果与特定且灵敏的气相色谱（GC）技术进行了比较。Halimetere对恒定浓度的不同VSC产生不同的双指数响应：相对响应率和灵敏度为硫化氢>甲基硫醚>二甲基硫醚。在硫化物检测器完全响应之前很久，口腔样品的瞬态峰值VSC浓度就达到了。呼气样本中初始总VSC的GC测量值比Halimeter（R）的峰值浓度高2.7 +/- 0.48倍。然而，Halimeter（R）的平台期测量值比GC的平台期测量值大25%。虽然GC和Halimeter（R）测量值呈正相关，但观察到明显的差异。在需要相对精确的VSC测量的研究中，GC是优选的技术。
The accuracy of the Halimeter(R), an inexpensive, simple instrument that measures total breath volatile sulfur compounds (VSCs), has not been adequately tested. We compared Halimeter(R) measurements with those obtained with a specific and sensitive gas chromatographic (GC) technique. The Halimetere, gave different, biexponential responses to a constant concentration of different VSCs: The relative response rate and sensitivity were hydrogen sulfide > methyl mercaptan > dimethylsulfide. The transient peak VSC concentration of oral samples was reached long before the sulfide detector fully responded. The GC measurement of initial total VSCs in breath samples was 2.7 +/- 0.48 times greater than the peak concentration of the Halimeter(R). However, the plateau phase measurement of the Halimeter(R) was 25% greater than that of GC. While GC and Halimeter(R) measurements positively correlated, appreciable differences were observed. In studies where relatively precise VSC measurements are required, GC is the preferable technique.