Organ donation during the COVID-19 pandemic
Organ donation during the COVID-19 pandemic
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DOI：
10.1111/ajt.16199
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发表时间：
2020-08-29
影响因子：
8.8
通讯作者：
Doyle, M. B. Majella
中科院分区：
文献类型：
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作者：
Ahmed, Ola;Brockmeier, Diane;Doyle, M. B. Majella
2019 年冠状病毒病 (COVID-19) 大流行是一种迅速变化的情况，政策发生了巨大的变化，人们普遍努力应对最初的危机并尽量减少其后果。为了确定在此期间器官捐献和移植的变化，我们向全美 19 个选定的器官获取组织 (OPO) 分发了一项匿名网络调查，比较了 2020 年 3 月至 5 月和 2019 年 3 月至 5 月的 90 天活动。 17 个 OPO 回复了该调查（回复率为 89.5%）。在当前大流行期间，器官授权减少了 11%（n = 1379 vs n = 1552，P = .0001）。移植器官恢复率下降了 17% (P = .0001)，移植器官数量进一步减少了 18% (P = .0001)。捐赠者死亡原因显示，在 COVID-19 期间，创伤减少了 4.5%，但药物滥用案件增加了 35%。所有 OPO 都报告了为应对这一流行病而进行的重大修改，限制了工作人员的现场存在，并过渡到通过电话方式与捐赠者家人进行通信。当前环境下的器官捐献已经发生了重大变化，但这种变化的长期影响仍不清楚。 COVID-19 时代的这些趋势需要进一步调查，以解决未满足的需求、计划对病毒采取适当的应对措施并减轻附带影响。
The coronavirus disease 2019 (COVID-19) pandemic is a rapidly changing circumstance with dramatic policy changes and universal efforts to deal with the initial crisis and minimize its consequences. To identify changes to organ donation and transplantation during this time, an anonymous web-based survey was distributed to 19 select organ procurement organizations (OPOs) throughout the United States comparing 90-day activity during March-May 2020 and March-May 2019. Seventeen OPOs responded to the survey (response rate of 89.5%). Organ authorization decreased by 11% during the current pandemic (n = 1379 vs n = 1552,P = .0001). Organ recovery for transplantation fell by 17% (P = .0001) with a further 18% decrease in the number of organs transplanted (P = .0001). Donor cause of death demonstrated a 4.5% decline in trauma but a 35% increase in substance abuse cases during the COVID-19 period. All OPOs reported significant modifications in response to the pandemic, limiting the onsite presence of staff and transitioning to telephonic approaches for donor family correspondence. Organ donation during the current climate has seen significant changes and the long-term implications of such shifts remain unclear. These trends during the COVID-19 era warrant further investigation to address unmet needs, plan for a proportionate response to the virus and mitigate the collateral impact.