Keratitis by a rare pathogen Colletotrichum gloeosporioides: A case report
Keratitis by a rare pathogen Colletotrichum gloeosporioides: A case report
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DOI：
10.1016/j.mycmed.2017.04.009
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发表时间：
2017-09-01
影响因子：
3.6
通讯作者：
Shah, S. R.
中科院分区：
文献类型：
--
作者：
Pote, S. T.;Chakraborty, A.;Shah, S. R.
刺盘孢菌属物种很少被报道为角膜炎或皮下病变的原因。我们描述的病人发生角膜炎后，眼外伤。根据形态特征和ITS区DNA序列分析，从角膜刮片中提取的样品生长有胶孢炭疽菌。患者接受局部应用阿替霉素B，随后接受伊曲康唑和那他霉素治疗。同时口服伏立康唑方案导致角膜溃疡完全消退。这份报告强调了这样一个事实，即早期和准确的识别和治疗可以解决罕见病原体C引起的角膜炎。胶孢菌(C)2017 Elsevier Masson SAS。All rights reserved.
Colletotrichum species have been reported infrequently as the cause of keratitis or subcutaneous lesions. The patient we describe developed keratitis after ocular trauma. The sample from the corneal scrapings grew Colletotrichum gloeosporioides as identified from morphological characters and DNA sequence of the 'Internal Transcribed Spacer' (ITS) region. The patient underwent topical application of amphotericin-B followed by itraconazole and natamycin treatment. Simultaneous oral voriconazole regimen leads to complete regression of corneal ulcer. This report highlights the fact that early and accurate identification and therapy can resolve keratitis caused by rare pathogen C. gloeosporioides. (C) 2017 Elsevier Masson SAS. All rights reserved.