Several Classes of Natural Products with Metal ion Chelating Ability
Several Classes of Natural Products with Metal ion Chelating Ability
复制标题
几类具有金属离子螯合能力的天然产物
DOI：
10.2174/1385272819666150709165210
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发表时间：
2015-01-01
影响因子：
2.6
通讯作者：
Wu, Bin
中科院分区：
文献类型：
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作者：
Shi, Yutong;Jiang, Wei;Wu, Bin
非共价相互作用，即离子对相互作用、氢键、阳离子-π相互作用和伦敦色散力被认为对分子识别具有根本性影响。金属离子与天然产物之间的关系已被广泛研究。许多天然产物具有离子螯合能力，如环肽、离子载体、铁载体、植物螯合素、黄酮类化合物以及其他类型的化合物，即多糖和寡糖。这些发现刺激了过去十年对离子螯合天然产物的广泛研究。本综述提供了对从天然来源获得的铁载体、植物螯合素和离子螯合类黄酮的更详细的了解。
Noncovalent interactions, namely ion pair interactions, hydrogen bonds, cation-pi interactions and London dispersion forces are considered to have a fundamental impact in molecular recognition. The relationship between metal ions and natural products has been extensively studied. A great number of natural products possess ion chelating ability, such as cyclic peptides, ionophores, siderophores, phytochelatins, flavonoids and other types of compounds, namely polysaccharides and oligosaccharides. These findings spurred extensive research on the ion chelating natural products over the past decade. This review provides a more detailed insight of siderophores, phytochelatins and ion chelating flavonoids obtained from natural sources.