Use of rapid diagnostic tests for diagnosis of malaria in the UK
Use of rapid diagnostic tests for diagnosis of malaria in the UK
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DOI：
10.1136/jcp.2005.032904
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发表时间：
2006-08-01
影响因子：
3.4
通讯作者：
Chiodini, P. L.
中科院分区：
文献类型：
--
作者：
Chilton, D.;Malik, A. N. J.;Chiodini, P. L.
背景：疟疾目前几乎完全通过临床实验室的显微镜检查来诊断。快速诊断试验（RDTs）的引入可能有助于实现疟疾寄生虫的快速检测，特别是在疟疾不常见或工作人员缺乏经验的情况下。目的：探讨RDT在英国实验室中的使用。方法：目前使用RDTs的调查在英国实验室订阅英国国家外部质量评估计划血液寄生虫学和血液学计划。结果：总体调查答复率为60.3%。RDTs被认为是首选，单独或与显微镜检查在31.2%的样本在正常工作时间内，并在44.3%的样本检查的呼叫。结论：在随叫随到的时间，使用RDTs观察到增加和RDTs改变了12%的实验室的诊断。然而，在英国没有观察到RDT使用的既定协议。一个协议，需要在实验室环境中进行验证的建议。
Background: Malaria is currently diagnosed almost exclusively by microscopy in clinical laboratories. The introduction of rapid diagnostic tests (RDTs) may be useful in achieving rapid detection of malaria parasites, especially in situations where malaria is not often seen or where staff are inexperienced.Aim: To explore the use of RDT in UK laboratories.Methods: The current use of RDTs was surveyed in UK laboratories subscribing to the United Kingdom National External Quality Assessment Scheme blood parasitology and haematology schemes.Results: An overall survey response rate of 60.3% was seen. RDTs were found to be the preferred choice, either alone or in conjunction with microscopy in 31.2% of the samples examined during normal working hours and in 44.3% of the specimens examined on call.Conclusions: During on-call hours, the use of RDTs was observed to increase and RDTs changed the diagnosis in 12% of laboratories. No established protocol for RDT use was, however, observed in the UK. A protocol that needs to be validated in the laboratory setting is suggested.