DIGESTION AND ABSORPTION IN THE HUMAN INTESTINE OF 3 SUGAR ALCOHOLS
DIGESTION AND ABSORPTION IN THE HUMAN INTESTINE OF 3 SUGAR ALCOHOLS
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DOI：
10.1016/0016-5085(90)90960-9
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发表时间：
1990-09-01
期刊：
影响因子：
29.4
通讯作者：
RAMBAUD, JC
中科院分区：
文献类型：
--
作者：
BEAUGERIE, L;FLOURIE, B;RAMBAUD, JC
消化和吸收的三种糖醇，消耗在三个相同的每日餐后剂量，在三个11天的时间内，在6名志愿者进行了评价。每个阶段包括3天适应期（在此期间增加糖醇剂量）、4天平衡期、2天粪便收集期和2天插管期。从第4天开始，每日给药量为30 g纯山梨糖醇、57 g含有30 g山梨糖醇的麦芽糖醇或69 g Lycasin 80/55（Roquette，Lestrem，France），其为也含有30 g山梨糖醇的氢化葡萄糖浆。单餐后通过抽吸测定糖醇及其组分的远端回肠输出量。在小肠中吸收的山梨糖醇的平均百分比在纯山梨糖醇剂量中显著高于含有麦芽糖醇和Lycasin 80/55的那些（79% ± 10%）。4%对64%。+-。4%和64%。5%，平均值±。SEM）。对于纯麦芽糖醇和Lycasin 80/55中所含的麦芽糖醇，消化的总麦芽糖醇的平均百分比没有差异（90% ± 0.0001），而对于纯麦芽糖醇和Lycasin 80/55中所含的麦芽糖醇，消化的总麦芽糖醇的平均百分比没有差异（90% ± 0.0001）。2%对86%。+-。2%）。粪便排泄的糖醇可以忽略不计，表明到达结肠的糖醇几乎完全被结肠植物群消化。摄入的糖醇的平均估计能量值（千卡/克）为3.58 ± 0.05。0.08对于山梨糖醇，约3.50 ±。0.07对于麦芽糖醇，在3.11 . ±. 0.08和3.54 ±。0.08 Lycasin 80/55由于本研究的实验条件模拟了三种糖醇的通常消耗方式，因此在所谓的无糖产品中长期消耗这些糖醇几乎不能节省热量。
The digestion and absorption of three sugar alcohols, consumed chronically in three identical daily postprandial doses, were evaluated in six volunteers during three 11-day periods. Each period included a 3-day adaptation period during which sugar alcohol doses were increased, a 4-day equilibration period, a 2-day stool collection period, and a 2-day intubation period. From day 4, the daily administered amounts were either 30 g pure sorbitol, 57 g maltitol containing 30 g sorbitol, or 69 g Lycasin 80/55 (Roquette, Lestrem, France), which is a hydrogenated glucose syrup also containing 30 g sorbitol. The distal ileal output of sugar alcohols and their components was determined by aspiration after a single meal. The mean percentage of sorbitol absorbed in the small intestine was significantly higher in pure sorbitol doses than in those containing maltitol and Lycasin 80/55 (79% .+-. 4% vs. 64% .+-. 4% and 64% .+-. 5%, mean .+-. SEM). The mean percentage of total maltitol digested was not different for pure maltitol and maltitol contained in Lycasin 80/55 (90% .+-. 2% vs. 86% .+-. 2%). Stool excretion of sugar alcohols was negligible, indicating that the sugar alcohols reaching the colon were almost completely digested by the colonic flora. The mean estimated energy values of the sugar alcohols ingested in kcal/g were 3.58 .+-. 0.08 for sorbitol, about 3.50 .+-. 0.07 for maltitol, and between 3.11 .+-. 0.08 and 3.54 .+-. 0.08 for Lycasin 80/55. Because the experimental conditions of this study mimicked the usual way of consumption of the three sugar alcohols, little calorie saving can be expected from the chronic consumption of these sugar alcohols in so-called sugar-free products.