Chernotherapy-related change in cognitive function: A conceptual model
Chernotherapy-related change in cognitive function: A conceptual model
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DOI：
10.1188/07.onf.981-994
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发表时间：
2007-09-01
影响因子：
1.9
通讯作者：
Insel, Kathleen C.
中科院分区：
文献类型：
--
作者：
Hess, Lisa M.;Insel, Kathleen C.
目的/目标：建立化疗相关认知功能变化的概念模型。数据来源：MEDLINEI（R）、CINAHL（R）、HealthStar和PsycINFO（R）数据库。数据综合：接受化疗的患者经常抱怨健忘、心不在焉和在执行各种日常任务时无法集中注意力。认知功能的变化被称为“化学脑”。作者对文献进行了检查，以调查概念之间的关系，并综合当前的knows.Conclusions：认知功能，定义为高阶心理过程，可能会改变沿着两个不同的和相互作用的途径：（a）癌症诊断，这可能会导致焦虑，压力，痛苦和抑郁症;和（B）癌症治疗的直接生理效应。化疗相关的认知功能变化的概念模型是由文献综述，说明前因，主持人，调解人，和后果，可能是相关的这个问题。当病人出现认知障碍时，当对化疗有一个全面的了解时，可以评估这些问题以进行干预-相关的认知变化的基础上的概念模型，继续通过良好的概念化和精心设计的研究告知。
Purpose/Objectives: To develop a conceptual model of chemotherapy-related changes in cognitive function.Data Sources: MEDLINEI (R), CINAHL (R), HealthStar, and PsycINFO (R) databases.Data Synthesis: Patients undergoing chemotherapy often complain of forgetfulness, absentmindedness, and an inability to focus when performing a variety of daily tasks. Changes in cognitive function have been referred to by the colloquial term "chemo-brain." The authors conducted an examination of the literature to investigate relationships among concepts and to synthesize current knowledge.Conclusions: Cognitive function, defined as higher-order mental processes, may be altered along two distinct and interacting pathways: (a) the cancer diagnosis, which can lead to anxiety, stress, distress, and depression; and (b) the direct physiologic effects of cancer treatment. The Chemotherapy-Related Change in Cognitive Function conceptual model is informed by a review of literature that illustrates antecedents, moderators, mediators, and consequences that may be relevant to this issue.Implications for Nursing: When a patient presents with cognitive complaints, the problems can be evaluated for intervention when an overall understanding exists of chemotherapy-related cognitive changes based on a conceptual model that continues to be informed through well-conceptualized and well-designed research.