Intermolecular copper-catalyzed carbon-hydrogen bond activation via carbene insertion
Intermolecular copper-catalyzed carbon-hydrogen bond activation via carbene insertion
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DOI：
10.1021/ja016798j
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发表时间：
2002-02-13
影响因子：
15
通讯作者：
Pérez, PJ
中科院分区：
文献类型：
--
作者：
Díaz-Requejo, MM;Belderraín, TR;Pérez, PJ
通式TpXCu （TpX=均硫膦酸配体）系列催化剂促进：CHCO2Et（重氮乙酸乙酯为碳源）在环烷烃和环醚的C−H键上插入，收率中至高。观察到这些催化剂的位阻与转化收率之间的相关性。
A series of catalysts of general formula TpXCu (TpX= homoscorpionate ligand) promote the insertion of :CHCO2Et (ethyl diazoacetate as the carbene source) into the C−H bonds of cycloalkanes and cyclic ethers in moderate to high yield. A correlation between the steric hindrance of these catalysts and the yield of the transformation has been observed.