Effect of a Mobile Phone Intervention on Quitting Smoking in a Young Adult Population of Smokers: Randomized Controlled Trial

Effect of a Mobile Phone Intervention on Quitting Smoking in a Young Adult Population of Smokers: Randomized Controlled Trial
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DOI:
10.2196/10893
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发表时间:
2018-10-01
影响因子:
5
通讯作者:
Brown, K. Stephen
Brown, K. Stephen
中科院分区:
医学2区
文献类型:
--
作者:
Baskerville, Neill Bruce;Struik, Laura Louise;Brown, K. Stephen

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背景:数字移动技术是向年轻人提供戒烟干预措施的一种很有前景的媒介,因为他们是这项技术的最大使用者。目的:本研究的目的是确定基于证据的智能手机戒烟应用程序Crush The Crave (CTC)与基于证据的自助指南on The Road to quit (OnRQ)相比,在降低年轻成年吸烟者吸烟率方面的功效。方法:在加拿大进行一项平行、双盲、随机对照试验,对CTC进行评价。在网上总共招募了1599名在未来30天内打算戒烟的年轻成年吸烟者(年龄在19 - 29岁),并随机分配到CTC或对照条件OnRQ中,为期6个月。在6个月的随访中,主要结局指标是自我报告的持续禁欲。结果:3个月和6个月的总随访率分别为57.41%(918/1599)和60.48%(967/1599)。此外,45.34%(725/1599)的参与者完成了基线、3个月和6个月的随访。意向治疗分析(最后一次随访)显示,6个月时持续戒断(N=1599)在CTC组中为7.8%(64/820),而在OnRQ组中为9.2%(72/779),差异无统计学意义(优势比;OR 0.83, 95% CI 0.59-1.18)。同样,在6个月时,CTC和OnRQ的30天点患病率戒断率分别为14.4%(118/820)和16.9%(132/779),差异无统计学意义(OR 0.82, 95% CI 0.63-1.08)。然而,与年轻人中11.5%的无辅助30天戒烟率相比,这些戒断率是有利的。在6个月的随访中,戒烟尝试和每天吸烟数量的二次测量没有显示组间有任何显著差异。在完成6个月随访的人群中,85.1%(359/422)的年轻成年吸烟者下载了CTC,而OnRQ的下载比例为81.8% (346/423),chi(2) (2)(1)(N=845) =1.6, P= 0.23。此外,OnRQ参与者报告的总体满意度水平显著更高(平均3.3 [SD 1.1] vs平均2.6 [SD 1.3]; t(644)= 6.87, P
Background: Digital mobile technology presents a promising medium for reaching young adults with smoking cessation interventions because they are the heaviest users of this technology. Objective: The aim of this study was to determine the efficacy of an evidence-informed smartphone app for smoking cessation, Crush the Crave (CTC), on reducing smoking prevalence among young adult smokers in comparison with an evidence-informed self-help guide, On the Road to Quitting (OnRQ).Methods: A parallel, double-blind, randomized controlled trial with 2 arms was conducted in Canada to evaluate CTC. In total, 1599 young adult smokers (aged 19 to 29 years) intending to quit smoking in the next 30 days were recruited online and randomized to receive CTC or the control condition OnRQ for a period of 6 months. The primary outcome measure was self-reported continuous abstinence at the 6-month follow-up.Results: Overall follow-up rates were 57.41% (918/1599) and 60.48% (967/1599) at 3 and 6 months, respectively. Moreover, 45.34% (725/1599) of participants completed baseline, 3-, and 6-month follow-up. Intention-to-treat analysis (last observation carried forward) showed that continuous abstinence (N=1599) at 6 months was not significantly different at 7.8% (64/820) for CTC versus 9.2% (72/779) for OnRQ (odds ratio; OR 0.83, 95% CI 0.59-1.18). Similarly, 30-day point prevalence abstinence at 6 months was not significantly different at 14.4% (118/820) and 16.9% (132/779) for CTC and OnRQ, respectively (OR 0.82, 95% CI 0.63-1.08). However, these rates of abstinence were favorable compared with unassisted 30-day quit rates of 11.5% among young adults. Secondary measures of quit attempts and the number of cigarettes smoked per day at 6-month follow-up did not reveal any significant differences between groups. For those who completed the 6-month follow-up, 85.1% (359/422) of young adult smokers downloaded CTC as compared with 81.8% (346/423) of OnRQ, chi(2) (2)(1(N=845))=1.6, P=.23. Furthermore, OnRQ participants reported significantly higher levels of overall satisfaction (mean 3.3 [SD 1.1] vs mean 2.6 [SD 1.3]; t(644)= 6.87, P