Weight suppression predicts total weight gain and rate of weight gain in outpatients with anorexia nervosa

Weight suppression predicts total weight gain and rate of weight gain in outpatients with anorexia nervosa
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DOI:
10.1002/eat.22425
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发表时间:
2015-11-01
影响因子:
5.5
通讯作者:
Joyce, Peter R.
Joyce, Peter R.
中科院分区:
医学2区
文献类型:
--
作者:
Carter, Frances A.;Boden, Joseph M.;Joyce, Peter R.

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本研究试图重复Wildes和Marcus,Behav res Ther,50,266-274,2012年的研究结果,即治疗前体重抑制水平越高,神经性厌食症患者的总体重增加越多,体重增加速度越快,并出现暴食症症状。35名妇女完成了门诊治疗和治疗后评估。体重抑制是成人一生最高身高体重与治疗前评估体重之间的差异。结果变量是治疗后评估前一个月的总体重增加、体重增加速度和暴食症状[使用饮食障碍检查进行评估(Fairburn等人,暴食:性质、评估和治疗)。纽约:吉尔福德,1993)。结果体重抑制与总体重增加和治疗后体重增加率呈正相关。回归模型显示,这种关联不能用协变量(神经性厌食症的发病年龄和治疗方式)来解释。在治疗后评估前一个月,体重抑制与暴食症症状没有明显的相关性,无论暴食症症状是作为连续变量还是二分变量来检验。讨论本研究强化了先前的发现,体重抑制预测了正在接受神经性厌食症治疗的患者的总体重增加和体重增加率。方法论上的问题可能解释了本研究未能发现体重抑制可以预测暴食症症状。神经性厌食症患者治疗前的体重抑制应常规评估,并可作为治疗计划的参考。(C)2015 Wiley期刊公司(INJ Eat Disord 2015;48:912-918)。
ObjectiveThe present study sought to replicate the finding of Wildes and Marcus, Behav Res Ther, 50, 266-274, 2012 that higher levels of weight suppression at pretreatment predict greater total weight gain, faster rate of weight gain, and bulimic symptoms amongst patients admitted with anorexia nervosa.MethodParticipants were 56 women with anorexia nervosa diagnosed by using strict or lenient weight criteria, who were participating in a randomized controlled psychotherapy trial (McIntosh et al., Am J Psychiatry, 162, 741-747, 2005). Thirty-five women completed outpatient treatment and post-treatment assessment. Weight suppression was the discrepancy between highest lifetime weight at adult height and weight at pretreatment assessment. Outcome variables were total weight gain, rate of weight gain, and bulimic symptoms in the month prior to post-treatment assessment [assessed using the Eating Disorders Examination (Fairburn et al., Binge-Eating: Nature, Assessment and Treatment. New York: Guilford, 1993)].ResultsWeight suppression was positively associated with total weight gain and rate of weight gain over treatment. Regression models showed that this association could not be explained by covariates (age at onset of anorexia nervosa and treatment modality). Weight suppression was not significantly associated with bulimic symptoms in the month prior to post-treatment assessment, regardless of whether bulimic symptoms were examined as continuous or dichotomous variables.DiscussionThe present study reinforces the previous finding that weight suppression predicts total weight gain and rate of weight gain amongst patients being treated for anorexia nervosa. Methodological issues may explain the failure of the present study to find that weight suppression predicts bulimic symptoms. Weight suppression at pretreatment for anorexia nervosa should be assessed routinely and may inform treatment planning. (c) 2015 Wiley Periodicals, Inc. (Int J Eat Disord 2015; 48:912-918).