The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans.
The Stressed Brain: Neural Underpinnings of Social Stress Processing in Humans.
复制标题
压力大脑：人类社会压力处理的神经基础。
DOI：
10.1007/7854_2021_281
复制
发表时间：
2022
影响因子：
--
通讯作者：
Lindquist,KristenA
中科院分区：
文献类型：
--
作者：
Muscatell,KeelyA;Merritt,CarringtonC;Cohen,JessicaR;Chang,Luke;Lindquist,KristenA
作为人类，我们经常面临各种社会压力。鉴于社会压力在影响身体和心理功能方面的既定作用，研究人员已经集中精力了解暴露于急性社会压力源引起的心理和生理变化。随着功能性磁共振成像（fMRI）的发展，最近的工作试图确定处理急性社会压力的神经相关性。在这篇综述中，我们提供了一个概述的研究社会压力处理的神经基础。具体来说，我们总结了研究，研究了三种类型的社会压力的神经基础，在文献中通常研究：社会排斥，社会评价和种族主义相关的压力。在我们对每种类型的社会压力源的讨论中，我们描述了用于诱导压力的方法，在调查这种类型的压力的研究中通常激活的大脑区域，以及对未来工作的建议。本文回顾了目前的文献，确定了活动在中线区域的前额叶和顶叶皮质，以及外侧前额叶区域，与处理社会排斥。在使用社会评价任务的研究中，经常会发现丘脑、额下回的活动。最后，种族主义相关的压力与腹外侧前额叶皮层和头端前扣带皮层的活动有关。最后，我们对这一领域的研究进行了“30,000英尺的观察”，为社会压力神经科学的未来研究提供了建议。
As humans, we face a variety of social stressors on a regular basis. Given the established role of social stress in influencing physical and psychological functioning, researchers have focused immense efforts on understanding the psychological and physiological changes induced by exposure to acute social stressors. With the advancement of functional magnetic resonance imaging (fMRI), more recent work has sought to identify the neural correlates of processing acute social stress. In this review, we provide an overview of research on the neural underpinnings of social stress processing to date. Specifically, we summarize research that has examined the neural underpinnings of three types of social stressors commonly studied in the literature: social rejection, social evaluation, and racism-related stress. Within our discussion of each type of social stressor, we describe the methods used to induce stress, the brain regions commonly activated among studies investigating that type of stress, and recommendations for future work. This review of the current literature identifies activity in midline regions in both prefrontal and parietal cortices, as well as lateral prefrontal regions, as being associated with processing social rejection. Activity in the insula, thalamus, and inferior frontal gyrus is often found in studies using social evaluation tasks. Finally, racism-related stress is associated with activity in the ventrolateral prefrontal cortex and rostral anterior cingulate cortex. We conclude by taking a “30,000-foot view” of this area of research to provide suggestions for the future of research on the neuroscience of social stress.