Sex in a dish: high-efficiency Toxoplasma pre-sexual development.

Sex in a dish: high-efficiency Toxoplasma pre-sexual development.
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盘中性:高效弓形虫性前发育。

DOI:
10.1016/j.pt.2024.01.009
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发表时间:
2024
影响因子:
9.6
通讯作者:
Knoll,LauraJ
Knoll,LauraJ
中科院分区:
医学1区
文献类型:
--
作者:
Hryckowian,NicoleD;Knoll,LauraJ

文献摘要

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Antunes等人通过靶向寄生虫表观遗传学和转录因子,成功培养出猫限期刚地弓形虫细胞。本报告的重点是寄生虫如何有效地转化为这些性前阶段。他们的工作是实现无猫重现t的重要一步。gondiisexual周期。
Antunes et al. successfully grew cat-restricted stages ofToxoplasma gondiiin cell culture by targeting parasite epigenetics and transcription factors. The highlight of this report is how efficiently parasites convert to these pre-sexual stages. Their work is an important step toward achieving feline-free recapitulation of theT. gondiisexual cycle.