Memory Deficits Precede Increases in Depressive Symptoms in Later Adulthood
Memory Deficits Precede Increases in Depressive Symptoms in Later Adulthood
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DOI：
10.1093/geronb/gbx183
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发表时间：
2019-09-01
影响因子：
6.2
通讯作者：
Ghisletta, Paolo
中科院分区：
文献类型：
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作者：
Aichele, Stephen;Ghisletta, Paolo
目的：我们研究了双向的，时间顺序的关联与年龄相关的变化，抑郁症状和memory.Method：数据来自107,599社区居住的成年人，年龄在49-90岁，谁参加了调查的健康，老龄化和退休在欧洲（共享）。抑郁症状与EURO-D量表进行了测量，记忆进行了评估为延迟回忆的10个单词的列表。参与者每隔2年接受最多5次评估。动态结构方程模型被用来估计纵向和时间顺序（铅滞后）抑郁症状和记忆performance.Results之间的关系：抑郁症状增加，记忆分数下降，在观察到的年龄范围内，62岁后最明显的恶化。这些长期变化呈中度负相关（r = -.53，p
Objectives: We examined bidirectional, time-ordered associations between age-related changes in depressive symptoms and memory.Method: Data came from 107,599 community-dwelling adults, aged 49-90 years, who participated in the Survey of Health, Ageing, and Retirement in Europe (SHARE). Depressive symptoms were measured with the EURO-D inventory, and memory was evaluated as delayed recall of a 10-word list. Participants were assessed up to five times at 2-year intervals. Dynamic structural equation models were used to estimate longitudinal and time-ordered (lead-lag) relations between depressive symptoms and memory performance.Results: Depressive symptoms increased and memory scores decreased across the observed age range, with worsening mostly evident after age 62 years. These long-term changes were moderately negatively correlated (r = -.53, p