Multiattribute and single-attribute utility functions for the health utilities index mark 3 system
Multiattribute and single-attribute utility functions for the health utilities index mark 3 system
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DOI：
10.1097/00005650-200202000-00006
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发表时间：
2002-02-01
期刊：
影响因子：
3
通讯作者：
Boyle, M
中科院分区：
文献类型：
--
作者：
Feeny, D;Furlong, W;Boyle, M
背景健康效用指数Mark 3（HU13）是一种通用的基于多属性偏好的健康状况和健康相关生活质量指标，广泛用作临床研究、人口健康调查、质量调整生命年估计和经济评估中的结局指标。HU13由健康状态的八个属性（或维度）组成：视觉、听觉、言语、运动能力、灵活性、情感、认知和疼痛，每个属性有5或6个级别，从高度受损到正常。我们的目标是提出一个多属性的效用函数和八个单属性效用函数的基础上，社区偏好的HU13系统。进行了两次偏好调查。一个是模型调查，收集了用于估计效用函数的偏好得分。另一个，直接调查，提供独立的分数，以评估效用函数的预测有效性。偏好测量包括在感觉温度计上获得的价值分数和使用机会板获得的标准赌博效用分数。加拿大安大略汉密尔顿普通人群（大于或等于16岁）的随机样本。估计获得了8个单属性的效用函数和一个整体的多属性效用函数。73种健康状态的效用评分与多属性功能评分的组内相关系数为0.88。HU13评分函数具有很强的理论和经验基础。它在预测直接测量的分数方面表现良好。HU13系统提供了一种实用的方法来获得基于社区偏好的效用分数。
BACKGROUND. The Health Utilities Index Mark 3 (HU13) is a generic multiattribute preference-based measure of health status and health-related quality of life that is widely used as an outcome measure in clinical studies, in population health surveys, in the estimation of quality-adjusted life years, and in economic evaluations. HU13 consists of eight attributes (or dimensions) of health status: vision, hearing, speech, ambulation, dexterity, emotion, cognition, and pain with 5 or 6 levels per attribute, varying from highly impaired to normal.OBJECTIVES. The objectives are to present a multiattribute utility function and eight single-attribute utility functions for the HU13 system based on community preferences.STUDY DESIGN. Two preference surveys were conducted. One, the modeling survey, collected preference scores for the estimation of the utility functions. The other, the direct survey, provided independent scores to assess the predictive validity of the utility functions.MEASURES. Preference measures included value scores obtained on the Feeling Thermometer and standard gamble utility scores obtained using the Chance Board.RESPONDENTS. A random sample of the general population (greater than or equal to16 years of age) in Hamilton, Ontario, Canada.RESULTS. Estimates were obtained for eight single-attribute utility functions and an overall multiattribute utility function. The intraclass correlation coefficient between directly measured utility scores and scores generated by the multiattribute function for 73 health states was 0.88.CONCLUSIONS. The HU13 scoring function has strong theoretical and empirical foundations. It performs well in predicting directly measured scores. The HU13 system provides a practical way to obtain utility scores based on community preferences.