SLEEP ALTERATIONS IN ISCHEMIC STROKE
SLEEP ALTERATIONS IN ISCHEMIC STROKE
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DOI：
10.1159/000116090
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发表时间：
1986-01-01
影响因子：
2.4
通讯作者：
LECHNER, H
中科院分区：
文献类型：
--
作者：
KORNER, E;FLOOH, E;LECHNER, H
对19例大脑中动脉区脑梗塞患者进行了移动脑电记录系统的睡眠调查。研究发现，与正常组相比，睡眠发生了显著变化。虽然卧床时间和睡眠时间有所增加，但总睡眠时间并没有同步增加，因此睡眠效率指数明显下降。这种数量参数的增加特别是由较长的NREM时间引起的，而REM睡眠被发现受到严重抑制。对于不同的NREM睡眠阶段，阶段0(夜间清醒时间)和阶段1增加，而阶段4减少。大脑半球之间的差异是指睡眠时间，特别是在右侧脑梗塞(由于NREM时间增加)和右脑病变的REM睡眠减少(REM/NREM比率恶化)中，睡眠时间增加。相反，在左半球梗死区，慢波睡眠(阶段4)被发现减少。这些结果支持右脑REM诱导和调节功能的假说，并将导致对睡眠控制机制的新理解。
In 19 patients with cerebral infarctions in the middle cerebral artery territory, investigations of sleep using a mobile EEG recording system were performed. Sleep was found to be markedly altered compared to a normal group. Although an increase of time in bed and sleep period time was observed, total sleep time did not rise in a parallel manner, so that a distinct reduction of the sleep efficiency index was found. This increase of quantitative parameters was particularly caused by a higher amount of NREM time, whereas REM sleep was found to be deeply suppressed. Regarding the different NREM sleep stages, stage 0 (time spent awake during the night) and stage 1 had increased, whereas stage 4 was reduced. Inter-hemispheric differences were noticed referring to the sleep period time, which was found to be increased particularly in right-sided infarctions (because of an increase of NREM time) and a reduction of REM sleep in lesions of the right hemisphere (worsening of the REM to NREM ratio). Slow-wave sleep (stage 4), on the contrary, was found to be decreased in infarctions of the left hemisphere. These results support the hypothesis of a REM-inducing and regulating function of the right hemisphere and will lead to a new understanding of sleep-controlling mechanisms.