BLOOD-PRESSURE AND ASSOCIATED FACTORS IN A RURAL KENYAN COMMUNITY

BLOOD-PRESSURE AND ASSOCIATED FACTORS IN A RURAL KENYAN COMMUNITY
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DOI:
10.1161/01.hyp.6.6.810
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发表时间:
1984-01-01
期刊:
影响因子:
8.3
通讯作者:
SEVER, PS
SEVER, PS
中科院分区:
医学1区
文献类型:
--
作者:
POULTER, N;KHAW, KT;SEVER, PS

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血压(BP)和相关因素进行了测定,在1737名男子在偏远的肯尼亚农业社区。收缩压没有显着上升,随着年龄的增长,直到54岁后,舒张压显示一个小的上升,随着年龄的增长。收缩压和舒张压与体重相关,与年龄无关。收缩压和舒张压与尿钠/钾呈显著正相关,与尿钾/肌酐呈显著负相关。收缩压和舒张压均与受教育年限显著相关,尿Na/K和Na/肌酐比值也是如此。K/肌酐比值与受教育年限呈负相关。血压和尿钠/肌酐比值显着低于自给农民与其他职业相比,和K/肌酐比值显着较高。对Luo族人的初步研究(2)显示,偶然尿电解质比值与24小时尿样的比值之间存在很强的相关性,这些人之间的Na排泄量差异大于个体内的差异。这些结果表明,BP和尿电解质的随意估计之间的关系可能是可识别的社区,那里有较少的日常饮食变化。与城市化相关的BP的一些变化可以通过饮食电解质的变化来介导。
Blood pressure (BP) and associated factors were determined in 1737 men in a remote Kenyan agricultural community. Systolic BP showed no significant rise with age until after 54 yr; diastolic BP showed a small rise with age. Both systolic and diastolic BP correlated with wt independent of age. Systolic and diastolic BP correlated positively with casual urinary Na/K and negatively with K/creatinine ratios. Both systolic and diastolic BP correlated significantly with the number of years of education, as did urinary Na/K and Na/creatinine ratios. K/creatinine ratios were negatively correlated with the number of yr of education. Blood pressure and urinary Na/creatinine ratios were significantly lower in subsistence farmers compared with those in other occupations, and K/creatinine ratios were significantly higher. Pilot studies (2) of Luo tribesmen showed a strong correlation between casual urinary electrolyte ratios and those derived from 24 h urine samples and a greater variance of Na excretion between these people than that found within individuals. These results suggest that a relationship between BP and casual urine electrolyte estimations may be identifiable in communities where there is less day-to-day dietary variation. Some of the changes in BP associated with urbanization could be mediated by changes in dietary electrolytes.