Microdamage adjacent to endosseous implants
Microdamage adjacent to endosseous implants
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DOI：
10.1016/s8756-3282(99)00151-9
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发表时间：
1999-08-01
期刊：
影响因子：
4.1
通讯作者：
Roberts, WE
中科院分区：
文献类型：
--
作者：
Huja, SS;Katona, TR;Roberts, WE
骨整合的骨内种植体附近的板层骨发生强烈的重塑。本研究的目的是比较骨内植入物周围骨的离体疲劳载荷后的微损伤累积，（a）放置后即刻（非适应骨）和（B）放置后12周愈合期（适应骨）。我们假设，在更顺应性的适应骨中的微损伤比在更老的非适应骨中的少。将无螺纹钛等离子喷涂（TPS）涂层骨内植入物放置到狗的股骨中段骨干中，并允许愈合12周。从前后方向切割骨块切片（每个切片包含一个植入物），得到包含外侧皮质和内侧皮质的植入物，用于测试不适应样本。在Bionix 858试验机上，对照样本（n = 14，适配和未适配）以0 N加载，实验样本（n = 13，适配; n = 14，未适配）以100 N加载，悬臂弯曲，在2 Hz和37 ℃下进行150，000次循环。用碱性品红对标本进行整体染色，获得120-140 μ m的切片。裂纹数密度（Cr.Dn = Cr.N/B.Ar，#/mm（2）），裂纹面密度（Cr.S.Dn = Tt.Cr.Le/B.Ar，mm/mm（2））和损伤面积百分比（Dm，Ar Cr.Ar x 100/B.Ar，mm（2）/mm（2））在x250处测量，统计学显著差异在压缩皮质上观察到Cr.Dn、Cr.S.Dn和Dm.Ar（p < 0.0001），表明种植体附近的适应骨累积的微损伤明显少于非适应骨。此外，适应的非负载对照样本的损伤比相应的非适应样本小约20倍。这项研究表明，骨内种植体附近的适应性骨对疲劳载荷具有相对的抵抗力。骨内种植体的高成功率可能是由于存在快速重塑区域，该区域保持组织顺应性并限制微损伤的发生。(C)1999年，Elsevier Science Inc. All rights reserved.
Intense remodeling occurs in lamellar bone adjacent to osseointegrated endosseous implants. The purpose of this study was to compare microdamage accumulation subsequent to ex vivo fatigue loading of bone that surrounds an endosseous implant, (a) immediately after placement (nonadapted bone) and (b) following a 12 week healing period after placement (adapted bone). We hypothesize that there is less microdamage in the more compliant adapted bone than in the older nonadapted bone, Nonthreaded titanium plasma sprayed (TPS)-coated endosseous implants were placed into dog midfemoral diaphyses and allowed to heal for 12 weeks. Block sections of bone, each containing one implant, were cut anteroposteriorly, resulting in an implant containing lateral cortex, and a medial cortex that was used for testing the nonadapted specimens. Control specimens (n = 14 each for adapted and nonadapted) were loaded at 0 N, Experimental specimens (n = 13, adapted; n = 14, nonadapted) were loaded at 100 N in cantilever bending for 150,000 cycles at 2 Hz, at 37 degrees C on a Bionix 858 testing machine. Specimens were bulk stained with basic fuchsin and 120-140 mu m sections were obtained. Crack numerical density (Cr.Dn = Cr.N/B.Ar, #/mm(2)), crack surface density (Cr.S.Dn = Tt.Cr.Le/B.Ar, mm/mm(2)), and percent damage area (Dm,Ar Cr.Ar x 100/B.Ar, mm(2)/mm(2)) were measured at x250, Statistically significant differences (p < 0.0001) were seen for Cr.Dn, Cr.S.Dn, and Dm.Ar on the compressed cortices suggesting that adapted bone near the implant accumulated significantly less microdamage than nonadapted bone. Also, the adapted nonloaded control specimens had approximately 20-fold less damage than the respective nonadapted specimens. This study suggests that the compliant adapted bone adjacent to endosseous implants is relatively resistant to fatigue loads. The high success rates of endosseous implants may be due to the presence of a rapidly remodeling region that maintains tissue compliance and limits microdamage initiation. (C) 1999 by Elsevier Science Inc. All rights reserved.