Threatening a rubber hand that you feel is yours elicits a cortical anxiety response
Threatening a rubber hand that you feel is yours elicits a cortical anxiety response
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DOI：
10.1073/pnas.0610011104
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发表时间：
2007-06-05
影响因子：
11.1
通讯作者：
Passingham, Richard E.
中科院分区：
文献类型：
--
作者：
Ehrsson, H. Henrik;Wiech, Katja;Passingham, Richard E.
身体所有权的感觉是自我意识的一个基本方面。潜在的神经机制可以通过使用错觉来研究，其中一个人通过刷人隐藏的真实的手并同步刷全视图中的人造手来感觉橡胶手是他或她自己的手。在这里，我们表明，当一个人的真实的手受到威胁时，对橡胶手的威胁可以在与焦虑和内感受性意识相关的大脑区域（大脑皮层和前扣带皮层）引起类似水平的活动。我们进一步表明，更强的感觉，所有权的假手，更强的威胁诱发的神经元反应的地区反映焦虑。此外，在所有受试者中，当手受到威胁时，反映所有权的多感觉区域的活动预测了内感受系统的活动。最后，我们发现内侧壁运动区有活动，反映了在受到威胁时收回假手的冲动。这些发现表明，假肢可以唤起与真实的肢体相同的感觉，并为橡胶手完全融入人体提供了客观的神经生理学证据。这些发现具有根本的重要性，因为它们表明身体所有权的感觉与内感受系统的变化有关。
The feeling of body ownership is a fundamental aspect of self-consciousness. The underlying neural mechanisms can be studied by using the illusion where a person is made to feel that a rubber hand is his or her own hand by brushing the person's hidden real hand and synchronously brushing the artificial hand that is in full view. Here we show that threat to the rubber hand can induce a similar level of activity in the brain areas associated with anxiety and interoceptive awareness (insula and anterior cingulate cortex) as when the person's real hand is threatened. We further show that the stronger the feeling of ownership of the artificial hand, the stronger the threat-evoked neuronal responses in the areas reflecting anxiety. Furthermore, across subjects, activity in multisensory areas reflecting ownership predicted the activity in the interoceptive system when the hand was under threat. Finally, we show that there is activity in medial wall motor areas, reflecting an urge to withdraw the artificial hand when it is under threat. These findings suggest that artificial limbs can evoke the same feelings as real limbs and provide objective neurophysiological evidence that the rubber hand is fully incorporated into the body. These findings are of fundamental importance because they suggest that the feeling of body ownership is associated with changes in the interoceptive systems.