Emulsion polymerization of vinyl acetate: safe optimization of a hazardous complex process.
Emulsion polymerization of vinyl acetate: safe optimization of a hazardous complex process.
复制标题
醋酸乙烯酯乳液聚合：危险复杂工艺的安全优化。
DOI：
10.1016/j.jhazmat.2011.04.066
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发表时间：
2011
影响因子：
13.6
通讯作者：
Renato Rota
中科院分区：
文献类型：
--
作者：
S. Copelli;M. Derudi;J. Sempere;E. Serra;A. Lunghi;C. Pasturenzi;Renato Rota
从安全和生产率的角度来看，快速和放热的间断乳液聚合工艺特别难以优化，因为会发生侧面不希望发生的反应(例如链转移到单体、反咬、叔基扩散、不成比例终止等)。常压下沸腾现象和稳定泡沫形成的危害。此外，在开始单体添加(即所需的反应)之前，需要相应数量的加载、加热和冷却步骤，这使得很难获得严格的产品质量重现性。在这些操作条件下，有必要采用合适的理论和实验相结合的方法，在实验室和工业规模上都能检测到最佳的工艺投药时间。在这项工作中，如何利用拓扑判据理论，结合合适的绝热量热计和RC1实验数据，在间接冷却的等周半间歇反应器中，安全地优化乙酸乙烯酯自由基乳液聚合合成聚乙酸乙烯酯。
Fast and exothermic discontinuous emulsion polymerization processes are particularly difficult to optimize from both safety and productivity point of view because of the occurrence of side undesired reactions (e.g. chain transfer to monomer, backbiting, propagation of tertiary radicals, termination by disproportion, etc.) and the hazards of boiling phenomena and stable foam formation under atmospheric pressure. Moreover, the relevant number of loading, heating and cooling steps, required before starting the monomer addition (that is, the desired reaction), makes a strict product quality reproducibility very difficult to obtain. Under these operating conditions, it is necessary to employ a suitable combined theoretical and experimental procedure able to detect the optimum process dosing time at both the laboratory and the industrial scale. In this work, it is shown how to use the topological criterion theory together with proper adiabatic calorimeter and RC1 experimental data to safely optimize the synthesis of polyvinyl acetate through the radical emulsion polymerization of vinyl acetate by the means of an indirectly cooled isoperibolic semibatch reactor.