Absorption of short wavelengths of endoillumination in indocyanine green solution: implications for internal limiting membrane removal
Absorption of short wavelengths of endoillumination in indocyanine green solution: implications for internal limiting membrane removal
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吲哚菁绿溶液中短波长内照明的吸收：对内界膜去除的影响
DOI：
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发表时间：
2003
期刊：
影响因子：
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通讯作者：
E. Uchio
中科院分区：
文献类型：
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作者：
K. Kadonosono;S. Takeuchi;Kazuro Yabuki;T. Yamakawa;A. Mekada;E. Uchio
目的测量玻璃体手术光源在吲哚菁绿色（ICG）溶液和平衡盐溶液（BSS）中对短波长的吸收系数。并确定这些吸收系数对ICG引起的视网膜光毒性的影响，玻璃体内界膜辅助去除法测定玻璃体内界膜的短波长吸收系数结果ICG溶液和BSS中的内照射光源对不同波长的吸收系数基本相同。ICG溶液的吸光度系数在400 nm处为0.18 cm-1，在450 nm处为0.03 cm-1。在BSS中，吸收系数在400 nm处为0.17 cm-1，在450 nm处为0.015 cm-1。400 nm和450 nm波长间吸光度无显著性差异（P>0.05）。ICG溶液在玻璃体内使用期间可能不会增强ICG辅助内界膜去除期间的视网膜光化学损伤。
PurposeTo measure the absorption coefficients of short wavelengths, irradiated by a light source used for vitreous surgery, in indocyanine green (ICG) solution and balanced salt solution (BSS), and to determine the implications of these absorption coefficients on retinal phototoxicity caused by ICG-assisted internal limiting membrane removal.MethodsThe absorption coefficients of short wavelengths irradiated by a commercially available light source used for vitreous surgery were measured in ICG solution and BSS using a dual-beam spectroradiometer.ResultsThe absorption coefficient of wavelengths irradiated by the endoillumination light source in ICG solution was almost the same as that obtained in BSS. The absorbance coefficients of the ICG solutions were 0.18 cm-1 at 400 nm and 0.03 cm-1 at 450 nm. In BSS, the absorption coefficients were 0.17 cm-1 at 400 nm and 0.015 cm-1 at 450 nm. No significant difference in absorbance was seen between 400 nm and 450 nm (P>0.05).ConclusionsThe absorption of wavelengths is not greater in ICG solution than in BSS. ICG solution during intravitreal use probably does not enhance retinal photochemical injury during ICG-assisted internal limiting membrane removal.