Transfer of early-cleaved embryos increases implantation rate in patients undergoing ovarian stimulation and ICSI-embryo transfer
Transfer of early-cleaved embryos increases implantation rate in patients undergoing ovarian stimulation and ICSI-embryo transfer
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DOI：
10.1016/s1472-6483(10)60519-6
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发表时间：
2004-02-01
影响因子：
4
通讯作者：
Bahçeci, M
中科院分区：
文献类型：
--
作者：
Çiray, HN;Ulug, U;Bahçeci, M
本研究验证了早期卵裂检查通过帮助选择最佳胚胎进行移植来提高妊娠率的假设。在接受卵胞浆内单精子注射（ICSI）周期的妇女中随机进行早期卵裂检查。在早期卵裂检查和未检查的胚胎之间没有观察到差异。当使用早期卵裂检查周期对早裂（EC）胚胎移植比晚裂（LC）胚胎移植产生更高妊娠率的假设进行验证时，发现EC胚胎移植比LC胚胎移植产生更高的着床率。在所有胚胎都是EC （100% EC）的移植中，与LC和未经检查的周期相比，较少胚胎的移植获得了更高的着床率。这些结果表明，当检查时，早期卵裂增加了ICSI患者的着床率。
The hypothesis that inspection for early cleavage improves pregnancy rate by aiding selection of the best embryos for transfer was tested in this study. Inspection for early cleavage was performed randomly in women undergoing intracytoplasmic sperm injection (ICSI) cycles. No differences were observed between early cleavage-inspected and uninspected embryos. When the hypothesis that transfer of early-cleaved (EC) embryos yields a higher pregnancy rate than transfer of late-cleaved (LC) embryos was tested using early cleavage-inspected cycles, it was found that transfer of EC embryos resulted in a higher implantation rate than transfer of LC embryos. In transfers for which all embryos were EC (100% EC), transfer of fewer embryos yielded a higher implantation rate compared with LC and uninspected cycles. These results indicate that, when inspected, early cleavage increases the implantation rate in ICSI patients.