Valve-sparing root replacement in patients with bicuspid versus tricuspid aortic valves
Valve-sparing root replacement in patients with bicuspid versus tricuspid aortic valves
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DOI：
10.1016/j.jtcvs.2018.10.151
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发表时间：
2019-07-01
影响因子：
6
通讯作者：
David, Tirone E.
中科院分区：
文献类型：
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作者：
Ouzounian, Maral;Feindel, Christopher M.;David, Tirone E.
目的：比较二尖瓣和三尖瓣联合二尖瓣根部置换术和三尖瓣根部置换术的疗效。方法：从1988年到2012年，连续333例患者(二尖瓣45例，三尖瓣288例)采用二尖瓣再植技术进行了二尖瓣根部置换术。初步分析是在1：3的二尖瓣：三尖瓣倾向性匹配的数据集上进行的，以缓解这两组之间的已知差异。在配对的数据集中，两组之间的平均年龄(二尖瓣：40+/-13岁；三尖瓣：41+/-14岁)和合并症的发生率相似。有二尖瓣的患者发生马凡综合征的可能性较小(二尖瓣：9%，三尖瓣：53%，P
Objectives: We sought to compare the outcomes of patients undergoing aortic valve-sparing root replacement with bicuspid versus tricuspid aortic valves.Methods: A total of 333 consecutive patients (bicuspid aortic valve, n = 45; tricuspid aortic valve, n = 288) underwent valve-sparing root replacement using the reimplantation technique from 1988 to 2012 at a single institution. The primary analysis was performed on a 1:3 bicuspid aortic valve: tricuspid aortic valve propensity-matched dataset to mitigate known differences between these 2 groups. In the matched, dataset, mean age (bicuspid aortic valve: 40 +/- 13 years; tricuspid aortic valve: 41 +/- 14) and rates of comorbidities were similar between groups. Patients with bicuspid aortic valves were less likely to have Marfan syndrome (bicuspid aortic valve: 9% vs tricuspid aortic valve: 53%, P