Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases
Sequenceserver: A Modern Graphical User Interface for Custom BLAST Databases
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DOI：
10.1093/molbev/msz185
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发表时间：
2019-12-01
影响因子：
10.7
通讯作者：
Wurm, Yannick
中科院分区：
文献类型：
--
作者：
Priyann, Anurag;Woodcroft, Ben J.;Wurm, Yannick
比较新获得的和以前已知的核苷酸和氨基酸序列是现代生物学研究的基础。BLAST是一种完善的比较工具，但在新数据集上使用具有挑战性。我们将以用户为中心的设计理念与可持续的软件开发方法相结合，创建了Sequenceserver，这是一个运行BLAST和可视化检查BLAST结果的工具，用于生物解释。Sequenceserver使用简单的算法来防止潜在的分析错误，并提供灵活的基于文本和视觉输出，以支持研究人员的生产力。我们的软件可以快速安装，供个人或共享服务器使用。
Comparing newly obtained and previously known nucleotide and amino-acid sequences underpins modern biological research. BLAST is a well-established tool for such comparisons but is challenging to use on new data sets. We combined a user-centric design philosophy with sustainable software development approaches to create Sequenceserver, a tool for running BLAST and visually inspecting BLAST results for biological interpretation. Sequenceserver uses simple algorithms to prevent potential analysis errors and provides flexible text-based and visual outputs to support researcher productivity. Our software can be rapidly installed for use by individuals or on shared servers.