Dynamics of transitions from anti-phase to multiple in-phase synchronizations in inhibitory coupled bursting neurons
Dynamics of transitions from anti-phase to multiple in-phase synchronizations in inhibitory coupled bursting neurons
复制标题
抑制耦合爆发神经元从反相同步到多个同相同步的转变动力学
DOI：
10.1007/s11071-018-4279-x
复制
发表时间：
2018-08-01
影响因子：
5.6
通讯作者：
Xue, Lei
中科院分区：
文献类型：
--
作者：
Jia, Bing;Wu, Yichen;Xue, Lei
抑制性偶联爆发神经元从反相同步到同相同步的转变对动物的运动节律非常重要。在这里，多个同相（完整），反相，相位同步突发模式的抑制耦合映射模型神经元与突发模式，这些模式之间的同步转换模拟在耦合强度和时间延迟的二维参数空间。时间延迟诱导的从反相到同相同步爆发行为的转变与龙虾口胃神经节抑制性耦联神经元的生物学实验中观察到的一致。此外，同相（完全）同步行为的爆发模式可以很好地解释与一个孤立的单个神经元的动态响应的负平方电流的作用时间，持续时间和强度类似的抑制性耦合电流的耦合强度和时间延迟调制。同步行为的爆发表现出与方形负电流诱导的单个神经元的爆发相同的模式，这是用快-慢变量解剖方法获得的。研究结果不仅揭示了时滞诱导的多重同步行为和同步跃迁的非线性现象，而且为基于映射的爆发模型神经元在不同时相对外部抑制刺激的不同动态响应提供了合理的解释.
Transition from anti-phase to in-phase synchronizations in inhibitory coupled bursting neurons is very important for locomotor rhythms of animals. Here, multiple in-phase (complete), anti-phase, and phase synchronous bursting patterns are simulated in inhibitory coupled map-based model neurons with bursting patterns, and synchronization transitions between these patterns are simulated in a two-dimensional parameter space of the coupling strength and time delay. Time delay-induced transition from anti-phase to in-phase synchronous bursting behaviors matches those observed in a biological experiment on the inhibitory coupled neurons in the stomatogastric ganglion of lobster. Furthermore, bursting patterns of the in-phase (complete) synchronous behaviors can be well interpreted with the dynamic responses of an isolated single neuron to a negative square current whose action time, duration, and strength are similar to those of the inhibitory coupling current modulated by the coupling strength and time delay. The burst of the synchronous behaviors manifests the same pattern as the square negative current-induced burst of the isolated single neuron, which is acquired with the fast–slow variable dissection method. The results not only present novel nonlinear phenomenon of the time delay-induced multiple synchronous behaviors and synchronization transitions, but also provide a reasonable interpretation with the different dynamic responses of map-based bursting model neuron to an external inhibitory stimulus applied at different phases.