Future perspectives of neurogenetics – in honor of Troy D. Zars (1967–2018)

Future perspectives of neurogenetics – in honor of Troy D. Zars (1967–2018)
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神经遗传学的未来展望 — 纪念 Troy D. Zars(1967 年 — 2018 年)

DOI:
10.1080/01677063.2020.1715975
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发表时间:
2020
影响因子:
1.9
通讯作者:
Wu, Chun-Fang
Wu, Chun-Fang
中科院分区:
医学4区
文献类型:
--
作者:
Gerber, Bertram;King, Elizabeth G.;Schulz, David;Tanimoto, Hiromu;Waddell, Scott;Wu, Chun-Fang

文献摘要

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本特刊致力于“神经遗传学的未来前景”,以纪念Troy D. Zars(1967-2018)。它旨在为我们理解适应行为是如何产生的,大脑在适应行为中扮演的角色,以及基因如何影响大脑-行为关系提供见解和灵感。我们希望这篇文章能传达特洛伊的兴奋之情,以及整个神经遗传学社区的兴奋之情,即现在有可能以前所未有的优雅、精确和完整的方式研究黑胃肠果蝇的这些基本问题。本期特刊还试图关注果蝇研究对其他物种研究的影响,反之亦然,并探讨果蝇研究、生物医学和实验心理学之间的共鸣案例。它是建立在这样一种理解之上的,即只有当我们尝试,而且只有当我们失败时,我们才能确定研究的边界。这应该促使我们寻求克服这些限制的方法,无论是通过更好的测量方法或实验操作,通过更巧妙的实验设计,还是通过提出概念上的改变。特洛伊体现了这样一个企业的创造力和乐观主义,加上永不磨灭的幽默感,以及在需要喝啤酒和烧烤的时候选择时机的能力。本期特刊分为四个部分。这些活动的重点是特洛伊作为一个人和一个科学家,回顾行为神经遗传学中令人兴奋的最新发现,展示鼓舞人心的新数据,并概述该领域的未来前景。
This special issue is dedicated to ‘Future Perspectives of Neurogenetics’ in honor of Troy D. Zars (1967–2018). It is intended to offer insight and inspiration for our understanding of how adaptive behavior arises, of the role the brain plays in adaptive behavior, and of how genes contribute to the brain-behavior relationship. We hope the issue conveys Troy’s excitement, and that of the neurogenetics community in general, about the possibilities now available for investigating these fundamental questions in Drosophila melanogaster with unprecedented elegance, precision and completeness.This special issue also attempts to be mindful of the implications of Drosophila research for studies in other species and vice versa and to explore cases of resonance between Drosophila research, biomedicine and experimental psychology. It was initiated on the understanding that we can only identify frontiers for enquiry if we try, and arguably only if we fail, to transgress them. This should prompt us to seek ways to overcome these limits, be it by better methods of measurement or of experimental manipulation, by more ingenious experimental design, or by proposing a conceptual change. Troy embodied the creativity and optimism of such an enterprise, combined with an unfailing sense of humor–and of timing for when a beer and a good barbecue was warranted instead. This special issue is organized into four sections. These focus on Troy as a person and scientist, on reviewing exciting recent findings in behavioral neurogenetics, on presenting inspiring new data and on outlining future perspectives for the field.