Tumor taxonomy for the developmental lineage classification of neoplasms.
Tumor taxonomy for the developmental lineage classification of neoplasms.
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DOI：
10.1186/1471-2407-4-88
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发表时间：
2004-11-30
期刊：
影响因子：
3.8
通讯作者：
Berman JJ
中科院分区：
文献类型：
--
作者：
Berman JJ
新的“肿瘤的发育谱系分类”在先前的出版物中进行了描述。分类很简单（整个层次只用39个分类器来描述），全面（为人类的每一个肿瘤提供了一个位置），并且与最近通过细胞遗传学和分子特征来描述肿瘤的尝试相一致。分类法是填充分类的实例列表。肿瘤分类学试图列出每个已知的人类肿瘤的每一个已知的术语。分类法为每个概念提供唯一的代码，并将相同概念下的同义术语分组。Perl脚本验证了分类法的连续草稿，以确保：1)每个术语在分类法中只出现一次；2)每个术语只出现在一个肿瘤分类中；3)每个概念代码在分类中只出现一个层次位置；4)包含分类和分类法的文件是格式良好的XML（可扩展标记语言）文档。该分类法目前包含122,632个不同的术语，包括5,376个肿瘤概念。每个概念平均有23个同义词。该分类法填充了“肿瘤的发育谱系分类”，并以XML文件的形式提供，目前长度为9兆字节以上。分类/分类法的表示形式列出了每个术语，然后是其代码，然后是其完整的祖先，该表示形式为平面文件，长度为19多兆字节。该分类法是最大的肿瘤命名法，其肿瘤名称的数量是其他医学命名法的两倍多，包括2004年版本的统一医学语言系统，医学临床术语系统化命名法，国家癌症研究所的同义词库和国际疾病肿瘤学分类版本。这篇手稿描述了一个全面的肿瘤分类，在一个唯一的代码编号下收集同义词术语，并将每个肿瘤分配到肿瘤层次结构中的单个类别。本文提供了整个分类和分类法的开放访问文件（XML和平面文件格式）。
The new "Developmental lineage classification of neoplasms" was described in a prior publication. The classification is simple (the entire hierarchy is described with just 39 classifiers), comprehensive (providing a place for every tumor of man), and consistent with recent attempts to characterize tumors by cytogenetic and molecular features. A taxonomy is a list of the instances that populate a classification. The taxonomy of neoplasia attempts to list every known term for every known tumor of man. The taxonomy provides each concept with a unique code and groups synonymous terms under the same concept. A Perl script validated successive drafts of the taxonomy ensuring that: 1) each term occurs only once in the taxonomy; 2) each term occurs in only one tumor class; 3) each concept code occurs in one and only one hierarchical position in the classification; and 4) the file containing the classification and taxonomy is a well-formed XML (eXtensible Markup Language) document. The taxonomy currently contains 122,632 different terms encompassing 5,376 neoplasm concepts. Each concept has, on average, 23 synonyms. The taxonomy populates "The developmental lineage classification of neoplasms," and is available as an XML file, currently 9+ Megabytes in length. A representation of the classification/taxonomy listing each term followed by its code, followed by its full ancestry, is available as a flat-file, 19+ Megabytes in length. The taxonomy is the largest nomenclature of neoplasms, with more than twice the number of neoplasm names found in other medical nomenclatures, including the 2004 version of the Unified Medical Language System, the Systematized Nomenclature of Medicine Clinical Terminology, the National Cancer Institute's Thesaurus, and the International Classification of Diseases Oncolology version. This manuscript describes a comprehensive taxonomy of neoplasia that collects synonymous terms under a unique code number and assigns each tumor to a single class within the tumor hierarchy. The entire classification and taxonomy are available as open access files (in XML and flat-file formats) with this article.
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影响因子：
14.9
作者：
Harris, MA;Clark, J;White, R
通讯作者：
White, R
影响因子：
3.8
作者：
Berman JJ
通讯作者：
Berman JJ
DOI：
10.1136/jamia.1997.0040484
发表时间：
1997-11-01
影响因子：
6.4
作者：
Humphreys, BL;McCray, AT;Cheh, ML
通讯作者：
Cheh, ML
影响因子：
3.5
作者：
Berman, Jules J
通讯作者：
Berman, Jules J
影响因子：
14.9
作者：
Galperin, MY
通讯作者：
Galperin, MY