Regional blood flow alterations after bovine fumaryl beta beta-crosslinked hemoglobin transfusion and nitric oxide synthase inhibition.
Regional blood flow alterations after bovine fumaryl beta beta-crosslinked hemoglobin transfusion and nitric oxide synthase inhibition.
复制标题
牛延胡索酰β-交联血红蛋白输注和一氧化氮合酶抑制后局部血流变化。
DOI：
10.1097/00003246-199604000-00003
复制
发表时间：
1996
影响因子：
8.8
通讯作者：
Koehler,RC
中科院分区：
文献类型：
--
作者：
Ulatowski,JA;Nishikawa,T;Matheson-Urbaitis,B;Bucci,E;Traystman,RJ;Koehler,RC
目的a）确定使用无细胞牛富马酰β-交联血红蛋白进行等容交换输血与使用携氧能力差的胶体溶液进行输血相比，是否会导致不同的局部血流分布模式。B）由于基于血浆的血红蛋白的潜在一氧化氮清除作用，确定在一氧化氮合酶抑制后血流差异是否减少。
Objectivesa) To determine whether isovolemic exchange transfusion with cell-free, bovine fumaryl beta beta-crosslinked hemoglobin results in a different pattern of regional blood flow distribution than transfusion with a poor oxygen-carrying, colloidal solution. b) Because of potential nitric oxide scavenging by plasma-based hemoglobin, to determine whether blood flow differences are reduced after nitric oxide synthase inhibition.Design