Associations Between Dietary Intake Before 6 Months of Age and Rapid Weight Gain Among HIV-exposed Uninfected Infants.
Associations Between Dietary Intake Before 6 Months of Age and Rapid Weight Gain Among HIV-exposed Uninfected Infants.
复制标题
暴露于 HIV 的未感染婴儿 6 个月前膳食摄入量与体重快速增加之间的关联。
DOI：
10.1097/mpg.0000000000001607
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发表时间：
2017
影响因子：
2.9
通讯作者：
Miller,TracieL
中科院分区：
文献类型：
--
作者：
Neri,Daniela;Oliveira,FernandaLC;Carvalho,AlineM;Somarriba,GabrielA;Scott,GwendolynB;Miller,TracieL
方法：在此横断面分析中，使用逻辑回归来确定与 RWG 相关的饮食因素，RWG 定义为从出生到评估（0.3-6 个月）的年龄别体重 z 评分变化 > 0.67 SD。其他协变量包括人口统计、出生、孕产妇和妊娠特征以及抗逆转录病毒暴露。结果：本次分析共纳入 86 名足月 HEU 婴儿，平均年龄为 3.4 个月（SD 1.8 个月）。百分之五十五的母亲肥胖。总体而言，39.5% 的婴儿表现出 RWG。在调整出生体重、当前年龄和能量摄入后，发现婴儿谷物摄入量与 RWG 之间存在显着相关性（比值比，3.52；95% 置信区间，1.02-12.10）。那些消耗最高三分之一蛋白质的婴儿在调整相同协变量后体重快速增加的可能性较小（比值比，0.15；95% 置信区间，0.02-0.94）。结论：婴儿早期体重增加的总体差异至少部分是由美国年轻 HEU 婴儿的婴儿喂养方式解释的。对 HEU 家庭的饮食咨询应强化美国儿科学会当前的喂养实践建议。
Methods:In this cross-sectional analysis, logistic regression was used to determine dietary factors associated with RWG defined as a> 0.67 SD change in weight-for-age z score from birth to assessment (0.3–6 months). Other covariates included demographics, birth, maternal and gestational characteristics, and antiretroviral exposures.Results:A total of 86 full-term HEU infants with a mean age of 3.4 months (SD 1.8 months) were included in this analysis. Fifty-five percent of mothers were obese. Overall, 39.5% of infants exhibited RWG. A significant association between consumption of infant cereal and RWG (odds ratio, 3.52; 95% confidence interval, 1.02–12.10) was found after adjusting for birth weight, current age, and energy intake. Those infants who consumed the highest tertile of protein were less likely to gain weight rapidly after adjusting for the same covariates (odds ratio, 0.15; 95% confidence interval, 0.02–0.94).Conclusions:Overall differences in weight gain during early infancy are at least partly explained by means of infant feeding in young HEU infants in the United States. Dietary counseling for families of HEU should reinforce current feeding practice recommendations of the American Academy of Pediatrics.