Side effects of aspirin

Side effects of aspirin
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阿司匹林的副作用

DOI:
10.1056/nejm197405232902111
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发表时间:
1974
期刊:
影响因子:
--
通讯作者:
F. Ingelfinger
F. Ingelfinger
中科院分区:
--
文献类型:
--
作者:
F. Ingelfinger

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从广泛的角度来看,阿司匹林可能是世界上最有用的止痛药。然而,医生对这种药物的看法似乎更多地受到其副作用的影响,而不是其主要效果。最近,在有报道称阿司匹林可能会降低心肌梗死的死亡率和频率后,阿司匹林的库存激增,从而扭转了因其大量不良反应而被起诉而导致的下降趋势。阿司匹林已经被认为或被证明可以干扰血小板功能,引起过敏反应,诱导肾上皮细胞脱落,启动胃和……。
Seen from a broad perspective, aspirin is probably the world's most useful analgesic. Yet the opinion physicians have of this agent appears to be influenced more by its side than by its principal effects. Recently, after reports that aspirin might decrease the mortality1 and frequency2 of myocardial infarction, the stock of aspirin surged upward, thus reversing a downward trend brought about by its indictment for a legion of adverse effects. Aspirin has been said or shown to interfere with platelet function, to cause allergic reactions in the sensitive, to induce exfoliation of renal epithelial cells, to initiate gastric and to . . .