Imaging: Dynamic imaging of gut function--allowing the blind to see.

Imaging: Dynamic imaging of gut function--allowing the blind to see.
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成像:肠道功能的动态成像——让盲人也能看见。

DOI:
10.1038/nrgastro.2014.149
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发表时间:
2014
期刊:
Nature reviews. Gastroenterology & hepatology
影响因子:
--
通讯作者:
Wang,ThomasD
Wang,ThomasD
中科院分区:
--
文献类型:
--
作者:
Joshi,BishnuP;Wang,ThomasD

文献摘要

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需要改进的方法来动态成像肠道行为,以评估是否存在神经肌肉退行性疾病。所谓的nanaps(可溶性纳米萘酞菁)已被开发用于口服给药,以穿过肠道,并为光声成像上的肠道运动可视化提供高对比度。此外,这些纳米颗粒的放射性示踪剂标记有助于使用 PET 进行多模式检测。
Improved methods are needed to dynamically image gut behaviour to assess whether neuromuscular degenerative disease is present. So-called nanonaps (soluble nanoformulated naphthalocyanines) have been developed for oral administration to pass through the intestines and provide high contrast for visualizing bowel motion on photoacoustic imaging. Moreover, radiotracer labelling of these nanoparticles facilitates multimodal detection using PET.