The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection.
The downregulation of GFI1 by the EZH2-NDY1/KDM2B-JARID2 axis and by human cytomegalovirus (HCMV) associated factors allows the activation of the HCMV major IE promoter and the transition to productive infection.
复制标题
EZH2-NDY1/KDM2B-JARID2 轴和人巨细胞病毒 (HCMV) 相关因子下调 GFI1,从而激活 HCMV 主要 IE 启动子并过渡到生产性感染。
DOI:
10.1371/journal.ppat.1004136
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发表时间:
2014
期刊:
影响因子:
6.7
通讯作者:
Tsichlis,PhilipN
中科院分区:
文献类型:
--
作者:
Sourvinos,George;Morou,Antigoni;Sanidas,Ioannis;Codruta,Ignea;Ezell,ScottA;Doxaki,Christina;Kampranis,SotiriosC;Kottakis,Filippos;Tsichlis,PhilipN