Infertility in American college alumnae

Infertility in American college alumnae
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DOI:
10.1016/s0020-7292(01)00381-2
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发表时间:
2001-06-01
影响因子:
3.8
通讯作者:
Wyshak, G
Wyshak, G
中科院分区:
医学4区
文献类型:
--
作者:
Wyshak, G

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目的:本文的目的是根据美国大学校友样本的自我报告,提供有关不孕症患病率、原因和治疗的数据。方法:以 3940 名年龄在 37 岁至 70 岁以上的美国大学校友为样本,完成了一份有关不孕症、不孕症原因、治疗结果的自填问卷。结果:在整个样本(n = 3940)中,3.1%(n = 121)患有原发性不孕症; 14.0% (n = 548) 患有继发性不孕并接受了治疗; 4.7% (n = 184) 尝试了 1 年多但没有成功,但未经治疗就怀孕了; 62.4%的人没有不孕问题; 16% (n = 616) 没有尝试怀孕。主要原因是“不明原因不孕”,占 43.5%;精子数量低或活力低,21.4%;和无排卵周期,20.3%。据报道,39.5% 的患者接受了克罗米芬治疗。治疗的总体成功率为 45%。当用克罗米芬治疗无排卵周期时,成功率最高。结论:在该美国女性样本中,原发性和继发性不孕症的患病率约为 17%,与撒哈拉以南非洲地区的观察结果相似。 (C) 2001 年国际妇产科联合会。版权所有。
Objective: The objective of this paper is to present data on prevalence of infertility, causes and treatments based on self-reports of a sample of American college alumnae. Methods: A sample of 3940 American college alumnae, ages 37 to over 70 years, completed a self-administered questionnaire relating to infertility, its causes, treatment treatment outcomes. Results: Of the entire sample (n = 3940), 3.1% (n = 121) had primary infertility; 14.0% (n = 548) had secondary infertility and were treated; 4.7% (n = 184) tried for more than 1 year without success but had pregnancies without treatment; and 62.4% had no problems with infertility; and 16% (n = 616) did not try to get pregnant. The major causes were 'unexplained infertility' reported by 43.5%; low sperm count or low motility, 21.4%; and anovulatory cycles, 20.3%. Treatment by clomid was reported by 39.5%. The overall success rate, resulting from treatment was 45%. The highest success rate occurred when anovulatory cycles were treated with clomid. Conclusion: Prevalence of primary and secondary infertility in this sample of American women is approximately 17%, similar to that observed for Sub-Saharan Africa. (C) 2001 International Federation of Gynecology and Obstetrics. All rights reserved.