Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis.
Responsiveness and Minimally Important Differences for 4 Patient-Reported Outcomes Measurement Information System Short Forms: Physical Function, Pain Interference, Depression, and Anxiety in Knee Osteoarthritis.
复制标题
DOI：
10.1016/j.jpain.2017.05.001
复制
发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Wang C
中科院分区：
文献类型：
--
作者：
Lee AC;Driban JB;Price LL;Harvey WF;Rodday AM;Wang C
患者报告结果测量信息系统（PROMIS）仪器可以为成年骨关节炎（OA）患者提供有效的、可解释的健康状况测量。然而，随着时间的推移，他们发现有意义的变化的能力是未知的。我们评估了四种PROMIS简短形式的反应性和最小重要差异（MID）：身体功能、疼痛干扰、抑郁和焦虑。我们分析了从我们的随机试验中比较太极和物理治疗的有症状的膝关节OA的成年人。使用基线和12周得分，通过测试PROMIS和遗留变化得分之间相关性的6个先验假设，根据共识标准评估响应性。如果确认≥5个假设，则认为反应性高，如果确认3或4个假设，则认为反应性中等。根据人们在遗留比较物上实现先前建立的MID的预期变化来评估MID。满足先验质量标准的最低和最高MID形成了每个PROMIS短表的MID范围。165名参与者主要为女性（70%）和白人（57%），平均年龄为61岁，体重指数为33kg/m2。PROMIS生理功能假说有5个，疼痛干扰假说、抑郁假说和焦虑假说分别有3个和4个。MID范围为：抑郁= 3.0-3.1；焦虑= 2.3 - -3.4;身体功能= 1.9 - -2.2;疼痛干扰= 2.35-2.4。PROMIS物理功能具有高反应性，抑郁、焦虑和疼痛干扰在成年膝关节OA患者中具有中等反应性。我们在该人群中建立了PROMIS的首个mid，为在未来的试验或临床实践中更好地应用或解释PROMIS提供了重要的参考标准。
Patient-Reported Outcomes Measurement Information System (PROMIS) instruments can provide valid, interpretable measures of health status among adults with osteoarthritis (OA). However, their ability to detect meaningful change over time is unknown. We evaluated the responsiveness and minimally important differences (MID) for four PROMIS Short Forms: Physical Function, Pain Interference, Depression, and Anxiety. We analyzed adults with symptomatic knee OA from our randomized trial comparing Tai Chi and physical therapy. Using baseline and 12-week scores, responsiveness was evaluated according to consensus standards by testing 6 a priori hypotheses of the correlations between PROMIS and legacy change scores. Responsiveness was considered high if ≥5 hypotheses were confirmed, and moderate if 3 or 4 were confirmed. MIDs were evaluated according to prospective change for people achieving previously-established MID on legacy comparators. The lowest and highest MIDs meeting a priori quality criteria formed an MID range for each PROMIS Short Form. Among 165 predominantly female (70%) and white (57%) participants, mean age was 61 years and body mass index was 33kg/m2. PROMIS Physical Function had 5 confirmed hypotheses and Pain Interference, Depression, and Anxiety had 3 or 4. MID ranges were: Depression=3.0–3.1; Anxiety=2.3–3.4; Physical Function=1.9–2.2; and Pain Interference=2.35–2.4. PROMIS Physical Function has high responsiveness, and Depression, Anxiety, and Pain Interference have moderate responsiveness among adults with knee OA. We established the first MIDs for PROMIS in this population, and provided an important standard of reference to better apply or interpret PROMIS in future trials or clinical practice.
登录
查看更多内容
DOI：
10.1002/art.21466
发表时间：
2005-10-15
期刊：
ARTHRITIS & RHEUMATISM-ARTHRITIS CARE & RESEARCH
影响因子：
--
作者：
Focht, BC;Rejeski, WJ;Messier, SP
通讯作者：
Messier, SP
影响因子：
13.3
作者：
Fries, James F.;Lingala, Bharathi;Siemons, Liseth;Glas, Cees A. W.;Cella, David;Hussain, Yusra N.;Bruce, Bonnie;Krishnan, Eswar
通讯作者：
Krishnan, Eswar
影响因子：
7.2
作者：
Eton, DT;Cella, D;Wood, WC
通讯作者：
Wood, WC
影响因子：
7.2
作者：
Cook, Karon F.;Jensen, Sally E.;Cella, David
通讯作者：
Cella, David
影响因子：
4.9
作者：
Fries JF;Krishnan E;Rose M;Lingala B;Bruce B
通讯作者：
Bruce B