Inductive heating property of graphene oxide-Fe3O4 nanoparticles hybrid in an AC magnetic field for localized hyperthermia
Inductive heating property of graphene oxide-Fe3O4 nanoparticles hybrid in an AC magnetic field for localized hyperthermia
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DOI：
10.1016/j.matlet.2011.11.013
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发表时间：
2012-02-01
影响因子：
3
通讯作者：
Tang, Jin-Tian
中科院分区：
文献类型：
--
作者：
Bai, Li-Zhong;Zhao, Dong-Lin;Tang, Jin-Tian
通过一种简单、可扩展的化学沉淀法成功地制备了超顺磁性氧化石墨烯纳米片-纳米Fe3O4(GO-Fe3O4)杂化材料。用透射电子显微镜、X射线衍射仪和傅立叶变换红外光谱对GO-Fe3O4杂化产物的结构进行了研究。研究了GO-Fe3O4杂化材料在交变磁场中的感热特性。评价了GO-Fe3O4杂化材料在肿瘤局部热疗中的应用前景。GO-Fe3O4杂化材料表现出超顺磁性，其比饱和磁化强度为47.56emug(-1)。将含有GO-Fe3O4杂化材料的生理盐水悬浮液暴露在交流磁场中500h后，温度为92.8℃。GO-Fe3O4杂化材料有望成为肿瘤局部热疗的良好热种子。(C)2011爱思唯尔B.V.保留所有权利。
The superparamagnetic graphene oxide nanosheets-Fe3O4 nanoparticles (GO-Fe3O4) hybrid has been successfully prepared via an easy and scalable chemical precipitation method. The structure of GO-Fe3O4 hybrid was investigated by transmission electron microscopy, X-ray diffraction and Fourier transform infrared spectroscopy. The inductive heat property of GO-Fe3O4 hybrid in an alternating current (AC) magnetic field was investigated. The potential of GO-Fe3O4 hybrid was evaluated for localized hyperthermia treatment of cancers. The GO-Fe3O4 hybrid exhibits a superparamagnetic behavior, its specific saturation magnetization, Ms is 47.56 emu g(-1). After exposed in the AC magnetic field for 500 s, the temperature of physiological saline suspension containing GO-Fe3O4 hybrid was 92.8 degrees C. The GO-Fe3O4 hybrid will be useful as good thermo-seeds for localized hyperthermia treatment of cancers. (C) 2011 Elsevier B.V. All rights reserved.