Temporal lobectomy in children with epilepsy.

Temporal lobectomy in children with epilepsy.
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癫痫儿童的颞叶切除术。

DOI:
10.3171/jns.1986.64.3.0371
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发表时间:
1986
影响因子:
4.1
通讯作者:
F. Sharbrough
F. Sharbrough
中科院分区:
医学1区
文献类型:
--
作者:
F. Meyer;W. Marsh;E. Laws;F. Sharbrough

文献摘要

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对29例男性和21例女性难治性癫痫患者行颞叶切除术的结果进行了分析,平均年龄15.8岁。癫痫发作的平均年龄为7.5岁,从发作到手术的平均时间为8.3年。术后27例(54%)无癫痫发作,12例(24%)仅有偶有意识消失的光晕,5例(10%)癫痫发作较少,6例(12%)无变化。因此,78%的人基本上没有癫痫发作,88%的人从手术中显著受益。手术前后韦氏智力量表评分无明显变化,但癫痫发作至手术的时间越短,言语智商和知觉智商改善的可能性越大。社会结果显著改善,很大比例的患者要么在学校,要么积极就业。对于患有难治性癫痫的儿童,建议及早考虑颞叶切除术。
The results of temporal lobectomy for medically refractory seizures are analyzed in 29 boys and 21 girls with a mean age of 15.8 years. The average age at onset of seizures was 7.5 years, and the time between onset and surgery averaged 8.3 years. Postoperatively, 27 patients (54%) were seizure-free, 12 patients (24%) had only occasional auras without loss of consciousness, five patients (10%) had fewer seizures, and six (12%) were unchanged. Therefore, 78% were essentially seizure-free and 88% benefited significantly from the operation. There was no significant change in the Wechsler Intelligence Scale scores before and after surgery; however, the shorter the time between seizure onset and surgery, the greater the likelihood of improvement in verbal and perceptual intelligence quotient. Social outcome was significantly improved, and a large percentage of patients were either in school or actively employed. Early consideration of temporal lobectomy in children with medically refractory seizures is recommended.