Characterizing the Micronuclear Gene Patterns in Ciliates
Characterizing the Micronuclear Gene Patterns in Ciliates
复制标题
纤毛虫微核基因模式的表征
DOI：
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发表时间：
2002
影响因子：
0.5
通讯作者：
G. Rozenberg
中科院分区：
文献类型：
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作者：
A. Ehrenfeucht;T. Harju;I. Petre;G. Rozenberg
摘要纤毛虫的基因组装过程是已知生物体中最复杂的DNA加工过程之一，从计算的角度来看，它是DNA计算的一个主要例子。在本文中，我们继续研究三种分子操作（ld，hi和dlad），这些操作被假定以分子内方式进行基因组装过程。特别是，我们专注于了解微核基因的IES/ MDS模式，这是纤毛虫基因组装研究的重要目标之一。我们成功地为三个分子操作的每个子集S表征了可以使用S中的操作组装的模式。这些结果增强了我们对微核基因结构（以及分子操作性质）的理解。他们允许一个建立微核基因的相似性和复杂性措施。
Abstract The process of gene assembly in ciliates is one of the most complex examples of DNA processing known in any organism, and it is fascinating from the computational point of view—it is a prime example of DNA computing in vivo. In this paper we continue to investigate the three molecular operations (ld, hi , and dlad ) that were postulated to carry out the gene assembly process in the intramolecular fashion. In particular, we focus on the understanding of the IES/ MDS patterns of micronuclear genes, which is one of the important goals of research on gene assembly in ciliates. We succeed in characterizing for each subset S of the three molecular operations those patterns that can be assembled using operations in S. These results enhance our understanding of the structure of micronuclear genes (and of the nature of molecular operations). They allow one to establish both similarity and complexity measures for micronuclear genes.