Cucurbitane-type triterpenoids from the leaves of Momordica charantia
Cucurbitane-type triterpenoids from the leaves of Momordica charantia
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DOI：
10.1080/10286020.2014.881801
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发表时间：
2014-03
影响因子：
1.7
通讯作者：
Yu-bo Zhang;Huan Liu;C. Zhu;Mao-xin Zhang;Yao-lan Li;B. Ling;Guocai Wang
中科院分区：
文献类型：
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作者：
Yu-bo Zhang;Huan Liu;C. Zhu;Mao-xin Zhang;Yao-lan Li;B. Ling;Guocai Wang
苦瓜叶乙醇提取物的植物化学研究。分离得到两个新的（1，2）和四个已知的（3-6）葫芦烷型三萜类化合物。通过IR、UV、MS、1D和2D NMR等波谱数据的分析，确定了它们的结构。并首次用改进的Mosher法、酸水解法和气相色谱法测定了苦参碱I（3）和II（4）的绝对构型。
Phytochemical investigation of the ethanol extract from the leaves of Momordica charantia L. led to the isolation of two new (1, 2) and four known (3–6) cucurbitane-type triterpenoids. Their structures were elucidated on the basis of extensive analyses of spectroscopic data including IR, UV, MS, 1D, and 2D NMR. Also the absolute configurations of momordicines I (3) and II (4) were determined for the first time by application of the modified Mosher's method, acid hydrolysis, and GC analysis.