In-Space Manufacturing and Resources - Earth and Planetary Exploration Applications
In-Space Manufacturing and Resources - Earth and Planetary Exploration Applications
复制标题
太空制造和资源 - 地球和行星探索应用
DOI：
10.1002/9783527830909.ch2
复制
发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Williams P
中科院分区：
文献类型：
--
作者：
Williams P
轨道航天的微重力环境为药物制造创造了新的机会。通过开发新的诊断工具、制造工艺、药物配方和药物管理，了解、恢复和维持航天员在太空极端环境中的健康，对地球上的医疗保健具有直接和长期的好处。航天药物和对策是天体药学的关键组成部分；太空药物的研究领域(包括稳定性和保质期以及PK/PD的变化)、太空药物(包括药物合成和药物配方的方法)以及太空药物(例如加速测试和结晶学)。为宇航员提供药物护理的能力将对支持地球极端和偏远环境中的人产生深远的好处，再加上我们对药理学、生理学、衰老和低地球轨道(LEO)实验中的诊断的理解的进步，将为真正的个性化药物奠定基础。
The microgravity environment of orbital spaceflight creates new opportunities for the manufacture of medicines. Understanding, restoring, and maintaining the health of astronauts in the extreme environment of space through the development of new diagnostic tools, manufacturing processes, medicines formulation, and medicines management have immediate and long‐term benefit for medical care on Earth.Space medicines and countermeasures are key components to astropharmacy; the field of research investigatingmedicines for space(covering issues such as stability and shelf life, and changes in PK/PD),medicines in space(including methods of drug synthesis and medicines formulation), andmedicines from space(accelerated testing and crystallography, for example).An ability to provide pharmaceutical care to astronauts will have profound benefits for the support of people in extreme and remote environments on Earth, and coupled with advances in our understanding of pharmacology, physiology, aging, and diagnostics from experiments in low Earth orbit (LEO), will underpin truly personalized medicines.